| Literature DB >> 558473 |
Abstract
In Munich the frequency of homozygotes of CAH (with and without salt losing syndrome) in the years 1963-1972 was 1; 9831. The CAH gen frequency was 1:99 and the frequency of heterozygote carriers was 1: 50. From these observations it was concluded that the number of undiagnosed boys suffering from CAH without salt losing syndrome must be very high. Assuming a sex ration of 1:1 for the children without salt losing syndrome the frequency of homozygotes (with and without salt losing syndrome) can be calculated to 1:7520. The statistical comparison of the frequency for Munich and for Zürich (Prader 1958) does not show a significant difference.Entities:
Mesh:
Year: 1977 PMID: 558473
Source DB: PubMed Journal: Klin Padiatr ISSN: 0300-8630 Impact factor: 1.349