Literature DB >> 557755

Elevated manganese levels associated with dementia and extrapyramidal signs.

R G Banta, W R Markesbery.   

Abstract

In a patient with elevated manganese levels, dementia, and an extrapyramidal syndrome, brain biopsy showed numerous neuritic plaques and neurofibrillary tangles typical of Alzheimer's disease. Manganese was elevated beyond toxic levels in serum, hair, urine, feces, and brain. The possible relationship of elevated manganese levels, dementia, and the extrapyramidal syndrome warrants further studies of similar cases.

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Year:  1977        PMID: 557755     DOI: 10.1212/wnl.27.3.213

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  22 in total

Review 1.  Role of manganese in neurodegenerative diseases.

Authors:  Aaron B Bowman; Gunnar F Kwakye; Elena Herrero Hernández; Michael Aschner
Journal:  J Trace Elem Med Biol       Date:  2011-10-01       Impact factor: 3.849

2.  Mechanisms of lead and manganese neurotoxicity.

Authors:  April P Neal; Tomas R Guilarte
Journal:  Toxicol Res (Camb)       Date:  2013-03-01       Impact factor: 3.524

Review 3.  Manganese and its role in Parkinson's disease: from transport to neuropathology.

Authors:  Michael Aschner; Keith M Erikson; Elena Herrero Hernández; Elena Herrero Hernández; Ronald Tjalkens
Journal:  Neuromolecular Med       Date:  2009       Impact factor: 3.843

4.  The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability.

Authors:  Diya Wang; Jianbin Zhang; Wenkai Jiang; Zipeng Cao; Fang Zhao; Tongjian Cai; Michael Aschner; Wenjing Luo
Journal:  Autophagy       Date:  2017-02-27       Impact factor: 16.016

5.  The effect of manganese-induced hypercholesterolemia on learning in rats.

Authors:  U K Sentürk; G Oner
Journal:  Biol Trace Elem Res       Date:  1996-03       Impact factor: 3.738

Review 6.  Role of transcription factor yin yang 1 in manganese-induced reduction of astrocytic glutamate transporters: Putative mechanism for manganese-induced neurotoxicity.

Authors:  Pratap Karki; Keisha Smith; James Johnson; Michael Aschner; Eunsook Lee
Journal:  Neurochem Int       Date:  2014-08-13       Impact factor: 3.921

7.  Signaling pathways mediating manganese-induced toxicity in human glioblastoma cells (u87).

Authors:  Shilpa Puli; James C K Lai; Kristina L Edgley; Christopher K Daniels; Alok Bhushan
Journal:  Neurochem Res       Date:  2006-10-17       Impact factor: 3.996

8.  Chronic manganese poisoning: a neuropathological study with determination of manganese distribution in the brain.

Authors:  M Yamada; S Ohno; I Okayasu; R Okeda; S Hatakeyama; H Watanabe; K Ushio; H Tsukagoshi
Journal:  Acta Neuropathol       Date:  1986       Impact factor: 17.088

9.  Human health risk assessment via drinking water pathway due to metal contamination in the groundwater of Subarnarekha River Basin, India.

Authors:  Soma Giri; Abhay Kumar Singh
Journal:  Environ Monit Assess       Date:  2015-02-03       Impact factor: 2.513

Review 10.  Manganese neurotoxicity: lessons learned from longitudinal studies in nonhuman primates.

Authors:  Neal C Burton; Tomás R Guilarte
Journal:  Environ Health Perspect       Date:  2008-10-03       Impact factor: 9.031

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