| Literature DB >> 557727 |
Y Furuichi, A LaFiandra, A J Shatkin.
Abstract
Reovirus mRNAs with 5'terminal m7GpppGm or GpppG are more stable than mRNA containing unblocked ppG 5'-ends when injected into Xenopus laevis oocytes or incubated in cell-free protein synthesising extracts of wheat germ and mouse L cells. The greater stability of mRNA with blocked 5' termini is not dependent upon translation but seems to result from protection against 5'-exonucleolytic degradation.Entities:
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Year: 1977 PMID： 557727 DOI： 10.1038/266235a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962