Literature DB >> 5573958

Hycanthone: a frameshift mutagen.

P E Hartman, K Levine, Z Hartman, H Berger.   

Abstract

Rapid spot-test screening of antischistosomal agents reveals that hycanthone is a potent frameshift mutagen while the closely related compound, miracil D, is nonmutagenic in Salmonella. Both hycanthone and miracil D are frameshift mutagens for T4 bacteriophage during growth in Escherichia coli.

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Year:  1971        PMID： 5573958     DOI： 10.1126/science.172.3987.1058

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  26 in total

1.  Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

Authors:  J McCann; E Choi; E Yamasaki; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1975-12       Impact factor: 11.205

2.  The mammalian spot test (Fellfleckentest) with mice.

Authors:  R Fahrig
Journal:  Arch Toxicol       Date:  1977-09-21       Impact factor: 5.153

3.  An improved bacterial test system for the detection and classification of mutagens and carcinogens.

Authors:  B N Ames; F D Lee; W E Durston
Journal:  Proc Natl Acad Sci U S A       Date:  1973-03       Impact factor: 11.205

Review 4.  Intestinal parasites.

Authors:  R Knight; M G Schultz; D W Hoskins; P D Marsden
Journal:  Gut       Date:  1973-02       Impact factor: 23.059

5.  Metabolic activation of mutagens in mammals host-mediated assay utilizing the induction of mitotic gene conversion in Saccharomyces cerevisiae.

Authors:  R Fahrig
Journal:  Agents Actions       Date:  1973-06

6.  Mutation and recombination experiments with yeast as prescreening tests for carcinogenic effects?

Authors:  H Marquardt
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1974

7.  Spontaneous auxotrophic and pigmented mutants occurring at high frequency in Bacillus pumilus NRRL B-3275.

Authors:  P S Lovett
Journal:  J Bacteriol       Date:  1972-11       Impact factor: 3.490

8.  Inhibition by metrifonate and dichlorvos of cholinesterases in schistosomes.

Authors:  E Bueding; C L Liu; S H Rogers
Journal:  Br J Pharmacol       Date:  1972-11       Impact factor: 8.739

9.  The role of mammals in the future of chemical mutagenesis research.

Authors:  W L Russell
Journal:  Arch Toxicol       Date:  1977-09-21       Impact factor: 5.153

10.  Cluster of genes controlling proline degradation in Salmonella typhimurium.

Authors:  B Ratzkin; J Roth
Journal:  J Bacteriol       Date:  1978-02       Impact factor: 3.490
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