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Literature DB >> 5573566

Synthesis of 5S and 4S RNA in metaphase-arrested HeLa cells.

Abstract

The continued synthesis of both 5S and 4S RNA in metaphase-arrested HeLa cells is demonstrated; 5S RNA is apparently synthesized at approximately 74 percent of the interphase rate, while 4S RNA is synthesized at approximately one-third the rate. The ratio of uridine incorporation to RNA methylation is used to correct for the alteration in the specific activity of the pyrimidine pool during metaphase arrest.

Entities: Chemical

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Year: 1971 PMID： 5573566 DOI： 10.1126/science.172.3986.947

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

11 in total

1. Mitotic repression of RNA polymerase II transcription is accompanied by release of transcription elongation complexes.

Authors: G G Parsons; C A Spencer
Journal: Mol Cell Biol Date: 1997-10 Impact factor: 4.272

2. Role of nonhistone chromosomal proteins in the restriction of mitotic chromatin template activity.

Authors: G Stein; J Farber
Journal: Proc Natl Acad Sci U S A Date: 1972-10 Impact factor: 11.205

3. Small nuclear RNAs synthesis in PHA-stimulated and nonstimulated human peripheral blood lymphocytes.

Authors: J Jaruzelska; W M Stolzmann; K Wiktorowicz; R Slomski
Journal: Mol Cell Biochem Date: 1981-03-27 Impact factor: 3.396

4. Intranuclear compartmentalization of DNA-dependent RNA polymerases: association of RNA polymerase I with nucleolar organizing chromosomes.

Authors: S Matsui; A A Sandberg
Journal: Chromosoma Date: 1985 Impact factor: 4.316

10. Induced changes in the rates of uridine- 3 H uptake and incorporation during the G 1 and S periods of synchronized Chinese hamster cells.

Authors: P J Stambrook; J E Sisken
Journal: J Cell Biol Date: 1972-03 Impact factor: 10.539

Synthesis of 5S and 4S RNA in metaphase-arrested HeLa cells.

1. Mitotic repression of RNA polymerase II transcription is accompanied by release of transcription elongation complexes.

2. Role of nonhistone chromosomal proteins in the restriction of mitotic chromatin template activity.

3. Small nuclear RNAs synthesis in PHA-stimulated and nonstimulated human peripheral blood lymphocytes.

4. Intranuclear compartmentalization of DNA-dependent RNA polymerases: association of RNA polymerase I with nucleolar organizing chromosomes.

5. Visualization of Transcription in early mouse embryos.

6. Nuclear envelope-associated resumption of RNA synthesis in late mitosis of HeLa cells.

7. The synthesis of ninety proteins including actin throughout the HeLa cell cycle.

8. A search for differential polypeptide synthesis throughout the cell cycle of HeLa cells.

9. Control of 5S RNA synthesis during early development of anucleolate and partial nucleolate mutants of Xenopus laevis.

10. Induced changes in the rates of uridine- 3 H uptake and incorporation during the G 1 and S periods of synchronized Chinese hamster cells.