Literature DB >> 557313

The surgeon, genetics, and cancer control: the Cancer Family Syndrome.

H T Lynch, R E Harris, C H Organ, H A Guirgis, P M Lynch, J F Lynch, E J Nelson.   

Abstract

A family manifesting the Cancer Family Syndrome has been evaluated extensively from the medical and genetic standpoint. Findings of excess occurrence of carcinoma of the colon and endometrium, multiple primary cancer, early age of onset, and autosomal dominant mode of genetic transmission mandate a program of increased surveillance and cancer education. Prophylactic surgical implications are provided for certain of these enormously high cancer risk patients.

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Year:  1977        PMID: 557313      PMCID: PMC1396131          DOI: 10.1097/00000658-197704000-00011

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  10 in total

1.  FREQUENCY OF MULTIPLE PRIMARY MALIGNANT NEOPLASMS ASSOCIATED WITH COLORECTAL CARCINOMA.

Authors:  H C POLK; J S SPRATT; H R BUTCHER
Journal:  Am J Surg       Date:  1965-01       Impact factor: 2.565

2.  Molecular biology, eugenics and euphenics.

Authors:  J LEDERBERG
Journal:  Nature       Date:  1963-05-04       Impact factor: 49.962

3.  Bowel function after colectomy for cancer, polyps, and diverticulitis.

Authors:  R C LILLEHEI; O H WANGENSTEEN
Journal:  J Am Med Assoc       Date:  1955-09-17

4.  Enzyme replacement therapy by renal allotransplantation in Fabry's disease.

Authors:  J T Clarke; R D Guttmann; L S Wolfe; J G Beaudoin; D D Morehouse
Journal:  N Engl J Med       Date:  1972-12-14       Impact factor: 91.245

5.  Familial cancer prevalence spanning eight years. Family N.

Authors:  H T Lynch
Journal:  Arch Intern Med       Date:  1974-11

6.  Sipple's syndrome: medullary thyroid carcinoma, pheochromocytoma, and parathyroid disease. Studies in a large family. NIH conference.

Authors:  H R Keiser; M A Beaven; J Doppman; S Wells; L M Buja
Journal:  Ann Intern Med       Date:  1973-04       Impact factor: 25.391

7.  Cancer family "G" revisited: 1895-1970.

Authors:  H T Lynch; A J Krush
Journal:  Cancer       Date:  1971-06       Impact factor: 6.860

8.  The cancer family syndrome and cancer control.

Authors:  H T Lynch; A J Krush
Journal:  Surg Gynecol Obstet       Date:  1971-02

Review 9.  The treatment of genetic disorders.

Authors:  S A Muller
Journal:  Arch Dermatol       Date:  1975-12

10.  Hereditary factors in cancer. Study of two large midwestern kindreds.

Authors:  H T Lynch; M W Shaw; C W Magnuson; A L Larsen; A J Krush
Journal:  Arch Intern Med       Date:  1966-02
  10 in total
  2 in total

1.  Family incidence of carcinoma of the colon and rectum in north-east Scotland.

Authors:  J L Duncan; J Kyle
Journal:  Gut       Date:  1982-02       Impact factor: 23.059

2.  Synchronous cancer of the colon: a case for more definitive resection in colon cancer.

Authors:  B B Anderson
Journal:  J Natl Med Assoc       Date:  1978-08       Impact factor: 1.798

  2 in total

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