Literature DB >> 5564393

Sepcific removal of in vivo antibody by extracorporeal circulation over an immunoadsorbent in gel.

I Schenkein, J C Bystryn, J W Uhr.   

Abstract

A method is described for preparation of a solid immunoadsorbent suspended in an agar gel. The immunoadsorbent in gel retains its specificity. Rabbits were injected with antibody or antigen, and an extracorporeal circulation was established through columns or funnels coated with such immunoadsorbents. It was shown that either antibody or antigen can be specifically and rapidly removed, and that no measurable amounts of antigen from the immunoadsorbent were released into the animals.

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Year:  1971        PMID： 5564393      PMCID： PMC292112          DOI： 10.1172/JCI106678

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  17 in total

1.  A method of trace iodination of proteins for immunologic studies.

Authors:  P J McConahey; F J Dixon
Journal:  Int Arch Allergy Appl Immunol       Date:  1966

2.  Plasmapheresis in severe Rh iso-immunization.

Authors:  J M Bowman; L J Peddle; C Anderson
Journal:  Vox Sang       Date:  1968       Impact factor: 2.144

3.  Capacity of pepsin-digested antibody to inhibit antibody formation.

Authors:  T W Tao; J W Uhr
Journal:  Nature       Date:  1966-10-08       Impact factor: 49.962

Review 4.  Water-insoluble derivatives of enzymes, antigens, and antibodies.

Authors:  I Silman; E Katchalski
Journal:  Annu Rev Biochem       Date:  1966       Impact factor: 23.643

5.  A method of removal of specific antibody from immunized rabbits.

Authors:  M W Graf; J W Uhr
Journal:  Proc Soc Exp Biol Med       Date:  1969-09

6.  The immunosuppressive effect of passively administered antibody IgG fragments.

Authors:  J C Cerottini; P J McConahey; F J Dixon
Journal:  J Immunol       Date:  1969-04       Impact factor: 5.422

7.  Purification of antibodies with immunoadsorbents prepared using bromoacetyl cellulose.

Authors:  J B Robbins; J Haimovich; M Sela
Journal:  Immunochemistry       Date:  1967-01

8.  Serum-mediated protection of neoplastic cells from inhibition by lymphocytes immune to their tumor-specific antigens.

Authors:  I Hellström; K E Hellström; C A Evans; G H Heppner; G E Pierce; J P Yang
Journal:  Proc Natl Acad Sci U S A       Date:  1969-02       Impact factor: 11.205

9.  Cell separation on antigen-coated columns. Elimination of high rate antibody-forming cells and immunological memory cells.

Authors:  H Wigzell; B Andersson
Journal:  J Exp Med       Date:  1969-01-01       Impact factor: 14.307

10.  Regulation of antibody formation by serum antibody. I. Removal of specific antibody by means of immunoadsorption.

Authors:  M W Graf; J W Uhr
Journal:  J Exp Med       Date:  1969-11-01       Impact factor: 14.307
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  10 in total

1.  Specific hemoperfusion through agarose acrobeads.

Authors:  S Margel; L Marcus
Journal:  Appl Biochem Biotechnol       Date:  1986-02       Impact factor: 2.926

2.  Specific suppression of antibody rebound after extracorporeal immunoadsorption. I. Comparison of single versus combination chemotherapeutic agents.

Authors:  D S Terman; R Garcia-Rinaldi; B Dannemann; D Moore; C Crumb; A Tavel; R Poser
Journal:  Clin Exp Immunol       Date:  1978-10       Impact factor: 4.330

3.  Prolonged antigen half-life in the lymphoid follicles of specifically immunized mice.

Authors:  J G Tew; T E Mandel
Journal:  Immunology       Date:  1979-05       Impact factor: 7.397

4.  Specific removal of DNA antibody with an immunoadsorbent.

Authors:  D S Terman; I Stewart; A Hoffmann; R Carr; R Harbeck
Journal:  Experientia       Date:  1974-12-15

5.  Editorial: Haemoperfusion for jaundice.

Authors: 
Journal:  Br Med J       Date:  1974-08-24

6.  Suitable hollow fibre immunobioreactors for specific ex vivo removal of antibodies and antigens from plasma.

Authors:  C Larue; V Gueraud; C Rivat
Journal:  Clin Exp Immunol       Date:  1985-10       Impact factor: 4.330

7.  Specific removal of DNA antibodies in vivo with an extracorporeal immuno-adsorbent.

Authors:  D S Terman; I Stewart; J Robinette; R Carr; R Harbeck
Journal:  Clin Exp Immunol       Date:  1976-05       Impact factor: 4.330

8.  Removing substances from blood by affinity chromatography. I. Removing bilirubin and other albumin-bound substances from plasma and blood with albumin-conjugated agarose beads.

Authors:  P H Plotz; P D Berk; B F Scharschmidt; J K Gordon; J Vergalla
Journal:  J Clin Invest       Date:  1974-03       Impact factor: 14.808

9.  Cellular interactions in immune regulation. Hapten-specific suppression by non-T cells and T cell mediated reversal of suppression.

Authors:  R H DeKruyff; B G Simonson; G W Siskind
Journal:  J Exp Med       Date:  1981-10-01       Impact factor: 14.307

10.  Binding of antigen by immunocytes. II. Effect of specific Ig on antigen binding by MOPC 315 cells.

Authors:  J C Bystryn; G W Siskind; J W Uhr
Journal:  J Exp Med       Date:  1975-06-01       Impact factor: 14.307
  10 in total

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