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Literature DB >> 5564387

Normalization of growth hormone hyperresponse to exercise in juvenile diabetics after "normalization" of blood sugar.

Abstract

The serum-growth hormone response to exercise is greater and occurs earlier in juvenile diabetics than in nondiabetics. A simple exercise test has been devised which unequivocally reveals the growth hormone hypersecretion of juvenile diabetics. Using this procedure we have shown that after a period of exceedingly strict metabolic control of the diabetes, complete normalization of growth hormone secretion is attained. It is concluded that the abnormalities in serum growth hormone found in juvenile diabetics are of a metabolic origin.

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 1971 PMID： 5564387 PMCID： PMC292105 DOI： 10.1172/JCI106671

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

8 in total

1. A SERUM GLUCOSE METHOD WITHOUT PROTEIN PRECIPITATION.

Authors: W A FETERIS
Journal: Am J Med Technol Date: 1965 Jan-Feb

2. Wick chromatography for rapid and reliable immunoassay of insulin, glucagon and growth hormone.

Authors: H Orskov; H G Thomsen; H Yde
Journal: Nature Date: 1968-07-13 Impact factor: 49.962

3. Diurnal serum growth hormone levels in poorly and well-controlled juvenile diabetics.

Authors: K Johansen; A P Hansen
Journal: Diabetes Date: 1971-04 Impact factor: 9.461

4. Colorimetric micro-determination of free fatty acids in plasma.

Authors: S Laurell; G Tibbling
Journal: Clin Chim Acta Date: 1967-04 Impact factor: 3.786

5. Notes on the glucose oxidase method.

Authors: N J Christensen
Journal: Scand J Clin Lab Invest Date: 1967 Impact factor: 1.713

6. Diabetes, diabetic angiopathy, and growth hormone.

Authors: K Lundbaek; N J Christensen; V A Jensen; K Johansen; T S Olsen; A P Hansen; H Orskov; R Osterby
Journal: Lancet Date: 1970-07-18 Impact factor: 79.321

7. Abnormal serum growth hormone response to exercise in juvenile diabetics.

Authors: A P Hansen
Journal: J Clin Invest Date: 1970-08 Impact factor: 14.808

8. Fatal case of polio-encephalitis due to poliomyelitis virus.

Authors: G H JENNINGS; J L HAMILTON-PATERSON; F O MacCALLUM
Journal: Br Med J Date: 1949-07-23

8 in total

24 in total

Review 6. [Diabetic angiopathy].

Authors: K Lundbaek
Journal: Acta Diabetol Lat Date: 1973 Mar-Apr

Normalization of growth hormone hyperresponse to exercise in juvenile diabetics after "normalization" of blood sugar.

1. A SERUM GLUCOSE METHOD WITHOUT PROTEIN PRECIPITATION.

2. Wick chromatography for rapid and reliable immunoassay of insulin, glucagon and growth hormone.

3. Diurnal serum growth hormone levels in poorly and well-controlled juvenile diabetics.

4. Colorimetric micro-determination of free fatty acids in plasma.

5. Notes on the glucose oxidase method.

6. Diabetes, diabetic angiopathy, and growth hormone.

7. Abnormal serum growth hormone response to exercise in juvenile diabetics.

8. Fatal case of polio-encephalitis due to poliomyelitis virus.

1. Splanchnic and leg exchange of glucose, amino acids, and free fatty acids during exercise in diabetes mellitus.

2. Development of insulin resistance in normal dogs following alloxan-induced insulin deficiency.

3. The role of abnormal hemorrheodynamics in the pathogenesis of diabetic retinopathy.

Review 4. Catecholamines and diabetes mellitus.

5. Metabolic and hormonal changes during exercise in healthy, diabetic and obese subjects.

Review 6. [Diabetic angiopathy].

7. [Growth hormone secretion in diabetic retinopathy].

8. Are the 'second generation' oral hypoglycemic agents really different?

9. Metabolic effects of acute and prolonged growth hormone excess in normal and insulin-deficient man.

Review 10. Search for a biochemical basis of diabetic microangiopathy.