| Literature DB >> 5560901 |
Abstract
1. Dopamine was shown to be released from the isolated lung of calves sensitized with horse serum by compound 48/80 and by specific antigen.2. Dopamine contracts the bovine pulmonary artery and pulmonary vein. Phentolamine, the alpha-adrenoceptor blocking agent, inhibits this activity of dopamine and also strongly reduces the Schultz-Dale response of the pulmonary vessels.3. The results are consistent with the suggestion that dopamine (together with histamine and 5-hydroxytryptamine) may participate in the pulmonary vasoconstriction associated with anaphylaxis in cattle.Entities:
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Year: 1971 PMID: 5560901 PMCID: PMC1665675 DOI: 10.1111/j.1476-5381.1971.tb07127.x
Source DB: PubMed Journal: Br J Pharmacol ISSN: 0007-1188 Impact factor: 8.739