Literature DB >> 5559905

Acetylcholine binding to Torpedo electroplax: relationship to acetylcholine receptors.

M E Eldefrawi, A G Britten, A T Eldefrawi.   

Abstract

Binding of [(3)H]acetylcholine to a particulate fraction of Torpedo electroplax was measured by equilibrium dialysis. Two high-affinity sites present on phospholipoproteins bound acetylcholine reversibly, and binding was blocked by nicotinic drugs. Characteristics of this binding suggest that these phospholipoproteins may be acetylcholine receptors.

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Year:  1971        PMID： 5559905     DOI： 10.1126/science.173.3994.338

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Regulation of binding properties of the nicotinic receptor protein by cholinergic ligands in membrane fragments from Torpedo marmorata.

Authors:  M Weber; T David-Pfeuty; J P Changeux
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205

2.  An ESR study of the postsynatpic membrane acetylcholinesterase of Torpedo marmorata electric organ.

Authors:  M Sentjurc; A Stalc; A O Zupancic
Journal:  Mol Cell Biochem       Date:  1976-12-10       Impact factor: 3.396

3.  Macromolecules from lobster axon membranes that bind cholinergic ligands and local anesthetics (recpetors-procaine-acetylcholine-nicotine-Na + and K + gates).

Authors:  J L Denburg; M E Eldefrawi; R D O'Brien
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

4.  Carbamylcholine and acetylcholine-sensitive, cation-selective ionophore as part of the purified acetylcholine receptor.

Authors:  A E Shamoo; M E Eldefrawi
Journal:  J Membr Biol       Date:  1975-12-04       Impact factor: 1.843

5.  Characterization and partial purification of the acetylcholine receptor from Torpedo electroplax.

Authors:  M E Eldefrawi; A T Eldefrawi
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

6.  Muscarinic cholinergic binding in rat brain.

Authors:  H I Yamamura; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

7.  Interaction of cholinergic ligands and local anesthetics with plasma membrane fragments from lobster axon.

Authors:  J K Marquis; D C Hilt; V A Papadeas; H G Mautner
Journal:  Proc Natl Acad Sci U S A       Date:  1977-06       Impact factor: 11.205
  7 in total

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