Literature DB >> 555583

Pharmacokinetics of Carbamazepine in man: a review.

S Pynnönen.   

Abstract

Gas-liquid chromatographic methods for determining plasma concentrations of the anticonvulsant drug carbamazepine are described. The pharmacokinetics of carbamazepine (absorption, protein binding, distribution, metabolism, and elimination) are reviewed, as well as the relationship between dose and plasma level and between plasma level and drug effects. Interactions with other drugs are noted.

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Year:  1979        PMID: 555583     DOI: 10.1097/00007691-197901030-00014

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN: 0163-4356            Impact factor:   3.681


  10 in total

Review 1.  Clinical pharmacokinetics of cerebrospinal fluid.

Authors:  M Bonati; J Kanto; G Tognoni
Journal:  Clin Pharmacokinet       Date:  1982 Jul-Aug       Impact factor: 6.447

2.  Population pharmacokinetics of carbamazepine in Singapore epileptic patients.

Authors:  E Chan; H S Lee; S S Hue
Journal:  Br J Clin Pharmacol       Date:  2001-06       Impact factor: 4.335

Review 3.  Anticonvulsant drugs. An update.

Authors:  M J Eadie
Journal:  Drugs       Date:  1984-04       Impact factor: 9.546

4.  Free concentration of carbamazepine and carbamazepine-10,11-epoxide in children and adults. Influence of age and phenobarbitone co-medication.

Authors:  R Riva; M Contin; F Albani; E Perucca; G Procaccianti; A Baruzzi
Journal:  Clin Pharmacokinet       Date:  1985 Nov-Dec       Impact factor: 6.447

5.  Hepatic enzyme induction and leucocyte delta-aminolaevulinic acid synthase activity: studies with carbamazepine.

Authors:  W G Rapeport; G T McInnes; G G Thompson; G Forrest; B K Park; M J Brodie
Journal:  Br J Clin Pharmacol       Date:  1983-08       Impact factor: 4.335

6.  Carbamazepine 10, 11 epoxide concentrations in epileptics on carbamazepine alone and in combination with other anticonvulsants.

Authors:  M J Brodie; G Forrest; W G Rapeport
Journal:  Br J Clin Pharmacol       Date:  1983-12       Impact factor: 4.335

7.  Effect of sodium valproate on carbamazepine disposition and psychomotor profile in man.

Authors:  G J Macphee; J R Mitchell; L Wiseman; A R McLellan; B K Park; G T McInnes; M J Brodie
Journal:  Br J Clin Pharmacol       Date:  1988-01       Impact factor: 4.335

8.  Effects of cimetidine on carbamazepine auto- and hetero-induction in man.

Authors:  G J Macphee; G G Thompson; G Scobie; E Agnew; B K Park; T Murray; K E McColl; M J Brodie
Journal:  Br J Clin Pharmacol       Date:  1984-09       Impact factor: 4.335

9.  Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans.

Authors:  M A Nitsche; K Fricke; U Henschke; A Schlitterlau; D Liebetanz; N Lang; S Henning; F Tergau; W Paulus
Journal:  J Physiol       Date:  2003-08-29       Impact factor: 5.182

10.  Differential effects on fast and slow spindle activity, and the sleep slow oscillation in humans with carbamazepine and flunarizine to antagonize voltage-dependent Na+ and Ca2+ channel activity.

Authors:  Amr Ayoub; Dominic Aumann; Anne Hörschelmann; Atossa Kouchekmanesch; Pia Paul; Jan Born; Lisa Marshall
Journal:  Sleep       Date:  2013-06-01       Impact factor: 5.849

  10 in total

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