Literature DB >> 555575

Decreased phenytoin levels in antineoplastic therapy.

R W Fincham, D D Schottelius.   

Abstract

A case history is reported illustrating the difficulties which may be encountered in maintaining seizure control in patients being treated with antineoplastic therapy. The maintenance of therapeutic serum levels of phenytoin during combined cis-platinum and bleomycin sulfate therapy suggests an absorptive defect, possibly related to damage of the intestinal mucosa. This defect did not appear to alter the absorption of primidone or phenobarbital, since increased dosages were not necessary to maintain these drugs within therapeutic ranges.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 555575     DOI： 10.1097/00007691-197901020-00009

Source DB:  PubMed          Journal:  Ther Drug Monit        ISSN： 0163-4356            Impact factor:   3.681


  10 in total

Review 1.  Treatment of concomitant illnesses in patients receiving anticonvulsants: drug interactions of clinical significance.

Authors:  P Loiseau
Journal:  Drug Saf       Date:  1998-12       Impact factor: 5.606

Review 2.  Pharmacokinetic drug interactions with phenytoin (Part II).

Authors:  R L Nation; A M Evans; R W Milne
Journal:  Clin Pharmacokinet       Date:  1990-02       Impact factor: 6.447

Review 3.  Drug interactions that matter. A critical reappraisal.

Authors:  G T McInnes; M J Brodie
Journal:  Drugs       Date:  1988-07       Impact factor: 9.546

Review 4.  Drug interactions with phenytoin.

Authors:  E Perucca; A Richens
Journal:  Drugs       Date:  1981-02       Impact factor: 9.546

5.  Pharmacokinetic interaction on valproic acid and recurrence of epileptic seizures during chemotherapy in an epileptic patient.

Authors:  Hiroaki Ikeda; Teruo Murakami; Mikihisa Takano; Tsuguru Usui; Kenji Kihira
Journal:  Br J Clin Pharmacol       Date:  2005-05       Impact factor: 4.335

Review 6.  Pharmacokinetic interactions with antiepileptic drugs.

Authors:  E Perucca
Journal:  Clin Pharmacokinet       Date:  1982 Jan-Feb       Impact factor: 6.447

7.  Influence of prophylactic anticonvulsant therapy on high-dose busulphan kinetics.

Authors:  M Hassan; G Oberg; M Björkholm; I Wallin; M Lindgren
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

8.  Fluctuation of serum phenytoin concentrations during autologous bone marrow transplant for primary central nervous system tumors.

Authors:  C Ghosh; H M Lazarus; J S Hewlett; R J Creger
Journal:  J Neurooncol       Date:  1992-01       Impact factor: 4.130

Review 9.  Antiepileptic drugs. A review of clinically significant drug interactions.

Authors:  P N Patsalos; J S Duncan
Journal:  Drug Saf       Date:  1993-09       Impact factor: 5.606

10.  Efficacy and tolerability of lacosamide for secondary epileptic seizures in patients with brain tumor: A multicenter, observational retrospective study.

Authors:  Juan Manuel Sepúlveda-Sánchez; Antonio Conde-Moreno; Manuel Barón; Javier Pardo; Gaspar Reynés; Antonio Belenguer
Journal:  Oncol Lett       Date:  2017-04-05       Impact factor: 2.967
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.