Literature DB >> 5549305

Eye lens color: formation and function.

S Zigman.   

Abstract

Aromatic amino acids are photooxidized by near-ultraviolet light to colored products that are bound very tightly to protein amino groups. The resulting colored proteins absorb near-ultraviolet light more strongly and are rendered more hydrophobic than the untreated compounds, and they fluoresce at 440 nanometers when excited at 360 nanometers. Coloration in the lenses of diurnally active animals (including man) may be caused by this reaction, and senile cataracts may result. Such changes in many other proteins (as in the skin and retina) could lead to more serious consequences.

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Year:  1971        PMID: 5549305     DOI: 10.1126/science.171.3973.807

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  8 in total

1.  Transmission of ocular media in labrid fishes.

Authors:  U E Siebeck; N J Marshall
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2000-09-29       Impact factor: 6.237

2.  An unsuccessful attempt to elicit orientation responses to linearly polarized light in hatchling loggerhead sea turtles (Caretta caretta).

Authors:  Lydia M Mäthger; Kenneth J Lohmann; Colin J Limpus; Kerstin A Fritsches
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-03-12       Impact factor: 6.237

3.  Inactivation of catalase by near ultraviolet light and tryptophan photoproducts.

Authors:  S Zigman; T Yulo; G A Griess
Journal:  Mol Cell Biochem       Date:  1976-06-15       Impact factor: 3.396

4.  The amino acid sequence of -crystallin (fraction II) from calf lens.

Authors:  L R Croft
Journal:  Biochem J       Date:  1972-07       Impact factor: 3.857

5.  A physiological analysis of color vision in batoid elasmobranchs.

Authors:  Christine N Bedore; Ellis R Loew; Tamara M Frank; Robert E Hueter; D Michelle McComb; Stephen M Kajiura
Journal:  J Comp Physiol A Neuroethol Sens Neural Behav Physiol       Date:  2013-12       Impact factor: 1.836

6.  Xanthurenic acid derivative formation in the lens is responsible for senile cataract in humans.

Authors:  H Z Malina; X D Martin
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1996-12       Impact factor: 3.117

7.  Patterns of pigmentation in the eye lens of the deep-sea hatchetfish, Argyropelecus affinis Garman.

Authors:  M McFall-Ngai; F Crescitelli; J Childress; J Horwitz
Journal:  J Comp Physiol A       Date:  1986-12       Impact factor: 1.836

8.  Deamination of 3-hydroxykynurenine in bovine lenses: a possible mechanism of cataract formation in general.

Authors:  H Z Malina; X D Martin
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1995-01       Impact factor: 3.117

  8 in total

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