Literature DB >> 5547727

New class of purine mutants of Chinese hamster ovary cells.

M W Taylor, M Souhrada, J McCall.   

Abstract

Mutants of Chinese hamster ovary cells (CHO/Pro(-)) were isolated after mutagenesis with N-methylnitrosoguanidine and selection by the bromodeoxyuridine technique. Six of these were mutants classified as purine-requiring. The metabolic block appears to be early in the purine biosynthetic pathway. The mutants do not appear to be genetically identical.

Entities:  

Mesh：

Substances：

Year:  1971        PMID： 5547727     DOI： 10.1126/science.172.3979.162

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  5-bromodeoxyuridine-DNA strand symmetry and the repair of photolytic breaks in Chinese hamster cell chromosomes.

Authors:  D J Roufa
Journal:  Proc Natl Acad Sci U S A       Date:  1976-11       Impact factor: 11.205

Review 2.  Utilization of somatic cell hybrids for genetic studies in man.

Authors:  K H Grzeschik
Journal:  Humangenetik       Date:  1973

3.  Induction and analysis of gene mutations in cultured mammalian somatic cells.

Authors:  E H Chu
Journal:  Genetics       Date:  1974-09       Impact factor: 4.562

4.  Induction of auxotrophic mutations by treatment of Chinese hamster cells with 5-bromodeoxyuridine and black light.

Authors:  E H Chu; N C Sun; C C Chang
Journal:  Proc Natl Acad Sci U S A       Date:  1972-11       Impact factor: 11.205

5.  Genetics of somatic mammalian cells: biochemical genetics of Chinese hamster cell mutants with deviant purine metabolism.

Authors:  D Patterson; F T Kao; T T Puck
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

6.  Purine mutants of mammalian cell lines. I. Accumulation of formylglycinamide ribotide by purine mutants of Chinese hamster ovary cells.

Authors:  R I Feldman; M W Taylor
Journal:  Biochem Genet       Date:  1974-11       Impact factor: 1.890

7.  Cellular reactions of O6-methylguanine, a product of some alkylating carcinogens.

Authors:  C T Miller; P D Lawley; S A Shah
Journal:  Biochem J       Date:  1973-10       Impact factor: 3.857
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.