| Literature DB >> 5542804 |
Abstract
Brains of rats undernourished from midgestation and killed at weaning contained 25 percent less norepinephrine than brains of adequately fed littermates. Perinatal undernutrition also suppressed the accumulation of brain dopamine. Paradoxically, the activity of tyrosine hydroxylase, the enzyme thought to be rate-limiting in catecholamine biosynthesis, was significantly increased in brains from undernourished animals.Entities:
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Year: 1971 PMID: 5542804 DOI: 10.1126/science.171.3975.1017
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728