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Literature DB >> 5539203

Radioimmunoassay for prostaglandins.

B M Jaffe, J W Smith, W T Newton, C W Parker.

Abstract

Antibodies to prostaglandin were obtained by immunization of rabbits with PGA(1), PGA(2), and PGE(1), protein conjugates of prostaglandins. The antibodies demonstrated specificity toward both the cyclopentane ring and the aliphatic side chains. With the use of these antibodies a highly sensitive radio-immunoassay capable of measuring less than picomolar amounts of PGA1, PGA2, and PGE1 has been developed.

Entities: Chemical Species

Mesh：

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Year: 1971 PMID： 5539203 DOI： 10.1126/science.171.3970.494

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

24 in total

1. The development of antisera to prostaglandins B2 and F2alpha and their analysis using solid-phase and double antibody radioimmunoassay methods.

Authors: K K Dighe; H A Emslie; L K Henderson; L Simon
Journal: Br J Pharmacol Date: 1975-12 Impact factor: 8.739

2. Release of prostaglandins from isolated cat spleen by angiotensin and vasopressin.

Authors: B Peskar; G Hertting
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1973 Impact factor: 3.000

3. Prostaglandins and glaucoma.

Authors: S M Podos; B M Jaffe; B Becker
Journal: Br Med J Date: 1972-10-28

4. Stimulated gastric prostaglandin output, and the effect of inhibition of prostaglandin synthetase, in the conscious cat.

Authors: R Baker; B M Jaffe; B Shaw; C W Venables
Journal: J Physiol Date: 1981-08 Impact factor: 5.182

5. Involvement of prostaglandin E1 in delayed-type hypersensitivity suppression induced with live Mycobacterium bovis BCG.

Authors: K Kato; K Yamamoto
Journal: Infect Immun Date: 1982-04 Impact factor: 3.441

Radioimmunoassay for prostaglandins.

1. The development of antisera to prostaglandins B2 and F2alpha and their analysis using solid-phase and double antibody radioimmunoassay methods.

2. Release of prostaglandins from isolated cat spleen by angiotensin and vasopressin.

3. Prostaglandins and glaucoma.

4. Stimulated gastric prostaglandin output, and the effect of inhibition of prostaglandin synthetase, in the conscious cat.

5. Involvement of prostaglandin E1 in delayed-type hypersensitivity suppression induced with live Mycobacterium bovis BCG.

6. Regulation of human immunoglobulin production in vitro by prostaglandin E2.

7. Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.

8. Endogenous prostaglandins and gastric secretion in the cat.

9. Radioimmunoassay measurement of prostaglandins E, A, and F in human plasma.

10. Autoregulation of bradykinin receptors and bradykinin-induced prostacyclin formation in human fibroblasts.