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Literature DB >> 5536863

Sensitivity of Hartmannella (Acanthamoeba) to 5-fluorocytosine, hydroxystilbamidine, and other substances.

Abstract

The effect of 24 anti-amoebic and other chemotherapeutic compounds on six strains of hartmannellid amoebae was studied by tissue culture, agar diffusion, and liquid axenic culture. Of the recognized anti-amoebic compounds only one inhibited growth of the amoebae, which were remarkable for their resistance. Two compounds, hydroxystilbamidine isethionate and 5-fluorocytosine, showed some amoebicidal activity while some others were inhibitory.

Entities: Chemical

Mesh：

Substances：

Year: 1970 PMID： 5536863 PMCID： PMC476862 DOI： 10.1136/jcp.23.8.649

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

9 in total

1. Pharmacology and therapeutic value of diamidine derivatives, particularly of 2-hydroxystilbamidine.

Authors: I SNAPPER; B SCHNEID; L McVAY; F LIEBEN
Journal: Trans N Y Acad Sci Date: 1952-05

2. A divided Petri dish for use with multipoint inoculators.

Authors: P H Sneath; M Stevens
Journal: J Appl Bacteriol Date: 1967-12

3. Study of a small amoeba from mammalian cell cultures infected with 'Ryan virus'.

Authors: D C Warhurst; J A Armstrong
Journal: J Gen Microbiol Date: 1968-02

4. Primary amoebic meningo-encephalitis: clinical, pathological and epidemiological features of six fatal cases.

Authors: R F Carter
Journal: J Pathol Bacteriol Date: 1968-07

5. Re-definition of the genus Acanthamoeba with descriptions of three species.

Authors: F C Page
Journal: J Protozool Date: 1967-11

6. Taxonomic criteria for limax amoebae, with descriptions of 3 new species of Hartmannella and 3 of Vahlkampfia.

Authors: F C Page
Journal: J Protozool Date: 1967-08

7. Primary amoebic meningoencephalitis in Britain.

Authors: J Apley; S K Clarke; A P Roome; S A Sandry; G Saygi; B Silk; D C Warhurst
Journal: Br Med J Date: 1970-03-07

8. Two cases of cryptococcal meningitis, one treated with 5-fluorocytosine.

Authors: J S Watkins; M J Campbell; D Gardner-Medwin; H R Ingham; I G Murray
Journal: Br Med J Date: 1969-07-05

9. Sensitivity to amphotericin B of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis.

Authors: R F Carter
Journal: J Clin Pathol Date: 1969-07 Impact factor: 3.411

9 in total

15 in total

1. Acanthamoeba keratitis.

Authors: D P Casemore; D C Warhurst
Journal: J Clin Pathol Date: 1992-04 Impact factor: 3.411

2. Differentiation of Acanthamoeba strains from infected corneas and the environment by using restriction endonuclease digestion of whole-cell DNA.

Authors: S Kilvington; J R Beeching; D G White
Journal: J Clin Microbiol Date: 1991-02 Impact factor: 5.948

Review 3. The Development of Drugs against Acanthamoeba Infections.

Authors: Ruqaiyyah Siddiqui; Yousuf Aqeel; Naveed Ahmed Khan
Journal: Antimicrob Agents Chemother Date: 2016-10-21 Impact factor: 5.191

4. In vitro and in vivo activity of 5-fluorocytosine on Acanthamoeba.

Authors: A R Stevens; W D O'Dell
Journal: Antimicrob Agents Chemother Date: 1974-09 Impact factor: 5.191

5. In vitro effects of amphotericin B on growth and ultrastructure of the amoeboflagellates Naegleria gruberi and Naegleria fowleri.

Authors: F L Schuster; E Rechthand
Journal: Antimicrob Agents Chemother Date: 1975-11 Impact factor: 5.191