Literature DB >> 55288

Bleomycin in advanced squamous cell carcinoma: a random controlled trial. Report of Medical Research Council Working Party on Bleomycin.

.   

Abstract

Bleomycin was compared with conventional cytotoxic drugs in the treatment of 70 patients with advanced squamous cell carcinoma; the primary deposit was in the head and neck in 50 patients and in the perineum or skin in 20. Thirty-four patients received bleomycin while 36 received other cytotoxic drugs. No significant difference was detected between the two groups either in the proportion showing tumour regression or in the survival rates. If bleomycin is to advance the treatment of squamous cell carcinoma it can be only in combination with other drugs or with radiotherapy.

Entities:  

Mesh：

Substances：

Year:  1976        PMID： 55288      PMCID： PMC1638494          DOI： 10.1136/bmj.1.6003.188

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  6 in total

1.  Treatment of unresectable and metastatic cutaneous squamous cell carcinoma.

Authors:  Lee D Cranmer; Candace Engelhardt; Sherif S Morgan
Journal:  Oncologist       Date:  2010-12-08

Review 2.  Idiopathic inflammatory myopathies.

Authors:  Ingrid E Lundberg; Manabu Fujimoto; Jiri Vencovsky; Rohit Aggarwal; Marie Holmqvist; Lisa Christopher-Stine; Andrew L Mammen; Frederick W Miller
Journal:  Nat Rev Dis Primers       Date:  2021-12-02       Impact factor: 52.329

Review 3.  Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy.

Authors:  Ambika Parmar; Michaelina Macluskey; Niall Mc Goldrick; David I Conway; Anne-Marie Glenny; Janet E Clarkson; Helen V Worthington; Kelvin Kw Chan
Journal:  Cochrane Database Syst Rev       Date:  2021-12-20

4.  [Intraarterial bleomycin therapy on squamous cell carcinomas of the oral cavity. Clinico-pathological investigations (author's transl)].

Authors:  W J Höltje; A Burkhardt; J O Gebbers; R Maerker
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1976-12-20

Review 5.  Therapy of advanced squamous cell carcinoma of the skin.

Authors:  Claudia Bejar; Eve Maubec
Journal:  Curr Treat Options Oncol       Date:  2014-06

6.  Anti-PD-1 antibody therapy for epithelial skin malignancies: An investigator-initiated, open-label, single-arm, multicenter, phase II clinical trial (NMSC-PD1 Study).

Authors:  Maki Ishii; Ikuko Hirai; Keiji Tanese; Takayuki Fusumae; Yoshio Nakamura; Keitaro Fukuda; Hiroshi Uchi; Kenji Kabashima; Atsushi Otsuka; Kenji Yokota; Naoya Yamazaki; Kenjiro Namikawa; Taku Fujimura; Tatsuya Takenouchi; Yuki Yamamoto; Mana Nishiguchi; Yasunori Sato; Masayuki Amagai; Takeru Funakoshi
Journal:  Medicine (Baltimore)       Date:  2020-10-30       Impact factor: 1.817
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.