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Literature DB >> 5511820

Studies of the effect of metoclopramide and apomorphine on gastric emptying and secretion in man.

Abstract

With oral and intravenous doses of metoclopramide there was no constant effect on the gastric emptying of test meals of glucose or sodium citrate, nor was secretion of acid by the stomach in response to test meals of glucose or sodium citrate affected. Apomorphine, in subnauseous doses (0.25 mg intravenously) slowed the gastric emptying of test meals containing sodium citrate, and 10 mg of intravenous metoclopramide abolished the slowing of gastric emptying caused by apomorphine.

Entities: Chemical Species

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Year: 1970 PMID： 5511820 PMCID： PMC1553172 DOI： 10.1136/gut.11.12.989

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

10 in total

1. Gastric emptying and secretion in man.

Authors: J N HUNT
Journal: Physiol Rev Date: 1959-07 Impact factor: 37.312

2. The regulation of gastric emptying of meals containing citric acid and salts of citric acid.

Authors: J N HUNT; M T KNOX
Journal: J Physiol Date: 1962-08 Impact factor: 5.182

3. Radiological observations of stomach changes accompanying threat of injection in a sample of peptic ulcer patients.

Authors: H JUNGMANN; P VENNING
Journal: Psychosom Med Date: 1955 Jan-Feb Impact factor: 4.312

4. Action of insulin hypoglycemia on motor and secretory functions of the digestive tract.

Authors: W H BACHRACH
Journal: Physiol Rev Date: 1953-10 Impact factor: 37.312

5. Physiology and pharmacology of vomiting.

Authors: H L BORISON; S C WANG
Journal: Pharmacol Rev Date: 1953-06 Impact factor: 25.468

6. The osmotic effects of some simple molecules and ions on gastric emptying.

Authors: J N Hunt; J D Pathak
Journal: J Physiol Date: 1960-12 Impact factor: 5.182

7. Metoclopramide ('Maxolon')--a new anti-emetic.

Authors: J A Trafford; A M Fisher; S Marshall; A H Douthwaite
Journal: Br J Clin Pract Date: 1967-09-09

8. Action of metoclopramide on gastric emptying and small bowel transit time.

Authors: W B James; R Hume
Journal: Gut Date: 1968-04 Impact factor: 23.059

9. The action of "metoclopramide" on gastric emptying: a radiological assessment.

Authors: G R Margieson; W A Sorby; H B Williams
Journal: Med J Aust Date: 1966-12-31 Impact factor: 7.738

10. Gastrointestinal effects of metoclopramide in man. In vitro experiments with human smooth muscle preparations.

Authors: M Eisner
Journal: Br Med J Date: 1968-12-14

10 in total

15 in total

Studies of the effect of metoclopramide and apomorphine on gastric emptying and secretion in man.

1. Gastric emptying and secretion in man.

2. The regulation of gastric emptying of meals containing citric acid and salts of citric acid.

3. Radiological observations of stomach changes accompanying threat of injection in a sample of peptic ulcer patients.

4. Action of insulin hypoglycemia on motor and secretory functions of the digestive tract.

5. Physiology and pharmacology of vomiting.

6. The osmotic effects of some simple molecules and ions on gastric emptying.

7. Metoclopramide ('Maxolon')--a new anti-emetic.

8. Action of metoclopramide on gastric emptying and small bowel transit time.

9. The action of "metoclopramide" on gastric emptying: a radiological assessment.

10. Gastrointestinal effects of metoclopramide in man. In vitro experiments with human smooth muscle preparations.

1. Gastric emptying of barium sulphate suspension compared with that of water.

2. The gastrointestinal tract in chemotherapy-induced emesis. A final common pathway.

3. Concentration effect studies with oral metoclopramide.

4. The influence of gastrointestinal transit on drug absorption in healthy volunteers.

5. Pharmacokinetic and concentration-effect studies with intravenous metoclopramide.

Review 6. Metoclopramide: a review of its pharmacological properties and clinical use.

7. Cisapride offsets dopamine-induced slowing of fasting gastric emptying.

8. The synaptic significance of metoclopramide induced dyskinetic-dystonic head and neck movements in pregnancy.

Review 9. Current concepts in diabetic gastroparesis.

Review 10. Metoclopramide. An updated review of its pharmacological properties and clinical use.