Literature DB >> 5507206

Norepinephrine metabolism in brainstem of spontaneously hypertensive rats.

Y Yamori, W Lovenberg, A Sjoerdama.   

Abstract

Concentrations of norepinephrine in lower brainstem and hypothalamus of genetically hypertensive rats are significantly lower than in control rats. There is a concomitant reduction (50 percent) in aromatic L-amino acid decarboxylase but not in tyrosine hydroxylase activity. A possible relation of this central catecholamine deficiency to the hypertension is discussed.

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Year:  1970        PMID： 5507206     DOI： 10.1126/science.170.3957.544

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  15 in total

1.  Effects of intraventricularly injected 6-hydroxydopamine on carotid sinus baroreceptor reflex in rabbits.

Authors:  S Takishita
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

2.  Decreased cAMP content of the hypothalamus of genetically hypertensive rats.

Authors:  G Schmid; K Hempel; A Heidland
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-05       Impact factor: 3.000

3.  Long-term depressor effects of noradrenaline and dopamine neurons transplanted into the third ventricle of the brain of salt-loaded hypertensive rats.

Authors:  R Hashimoto; F Kimura
Journal:  Experientia       Date:  1988-06-15

4.  Structural basis for resetting of baroreceptor regulation in spontaneously hypertensive rats (SHR).

Authors:  D Wellens; M Borgers; A Verheyen
Journal:  Experientia       Date:  1973-10-15

5.  Serum dopamine- -hydroxylase in spontaneously hypertensive rats.

Authors:  T Nagatsu; T Kato; H Kuzuya; H Umezawa; M Matsuzaki; T Takeuchi
Journal:  Experientia       Date:  1972-08-15

6.  Brain catecholamines and organ weight of mice genetically selected for high and low blood pressure.

Authors:  G Schlager; R Freeman; S S Sustarsic
Journal:  Experientia       Date:  1979-01-15

7.  Catecholamine synthetic enzymes of spontaneously hypertensive rats and microbial hypotensive products.

Authors:  T Nagatsu; K Mizutani; I Nagatsu; H Umezawa; M Matsuzaki
Journal:  Mol Cell Biochem       Date:  1973-05-11       Impact factor: 3.396

8.  Genetic regulation of catecholamine synthesis, storage and secretion in the spontaneously hypertensive rat.

Authors:  M L Jirout; R S Friese; N R Mahapatra; M Mahata; L Taupenot; S K Mahata; V Kren; V Zídek; J Fischer; H Maatz; M G Ziegler; M Pravenec; N Hubner; T J Aitman; N J Schork; D T O'Connor
Journal:  Hum Mol Genet       Date:  2010-04-08       Impact factor: 6.150

9.  Markedly elevated specific renin levels in the adrenal in genetically hypertensive rats.

Authors:  M Naruse; T Inagami
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

10.  Genetically hypertensive rats: relationship between the development of hypertension and the changes in norepinephrine turnover of peripheral and central adrenergic neurons.

Authors:  K Nakamura; M Gerold; H Thoenen
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1971
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