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Literature DB >> 550491

Isoniazid pharmacokinetics in kwashiorkor.

Abstract

Isoniazid plasma half-life and clearance rates were studied in children with kwashiorkor before and after nutritional rehabilitation. Isoniazid half-life rates fell and clearance increased with nutritional rehabilitation. The changes documented in this report are not an indication that isoniazid therapy should be altered in malnourished children, but may indicate that this should be done in malnourished adults.

Entities: Chemical Species

Mesh：

Substances：
Isoniazid

Year: 1979 PMID： 550491

Source DB: PubMed Journal: S Afr Med J

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Cited

12 in total

1. Nutrition and drug disposition.

Authors: S Mehta
Journal: Indian J Pediatr Date: 1986 Mar-Apr Impact factor: 1.967

2. Risk Factors of Hepatotoxicity During Anti-tuberculosis Treatment.

Authors: A C Anand; A K Seth; M Paul; P Puri
Journal: Med J Armed Forces India Date: 2011-07-21

Review 3. Hepatotoxicity Related to Anti-tuberculosis Drugs: Mechanisms and Management.

Authors: Vidyasagar Ramappa; Guruprasad P Aithal
Journal: J Clin Exp Hepatol Date: 2012-12-20

4. Influence of age, sex and body weight on the dapsone acetylation phenotype.

Authors: P A Philip; S L Gayed; H J Rogers; P Crome
Journal: Br J Clin Pharmacol Date: 1987-06 Impact factor: 4.335

5. Proceeding of the British Pharmacological Society, Clinical Pharmacology Section, 16-18th December, 1980, University of London. Abstracts.

Authors:
Journal: Br J Clin Pharmacol Date: 1981-04 Impact factor: 4.335

Isoniazid pharmacokinetics in kwashiorkor.

1. Nutrition and drug disposition.

2. Risk Factors of Hepatotoxicity During Anti-tuberculosis Treatment.

Review 3. Hepatotoxicity Related to Anti-tuberculosis Drugs: Mechanisms and Management.

4. Influence of age, sex and body weight on the dapsone acetylation phenotype.

5. Proceeding of the British Pharmacological Society, Clinical Pharmacology Section, 16-18th December, 1980, University of London. Abstracts.

6. Acetanilide pharmacokinetics in kwashiorkor.

Review 7. A systematic review of pharmacokinetics studies in children with protein-energy malnutrition.

Review 8. Hepatotoxic effects of therapies for tuberculosis.

9. Antituberculosis treatment-induced hepatotoxicity: role of predictive factors.

Review 10. Influences of diet and nutrition on clinical pharmacokinetics.