Literature DB >> 549682

Chemical structure and antifungal activity of a number of triterpenoids.

M M Anisimov, V V Shcheglov, L I Strigina, N S Chetyrina, N I Uvarova, G I Oshitok, N G Alad'ina, L P Vecherko, A D Zorina, L G Matyukhina, I A Saltykova.   

Abstract

Antifungal activity was tested in 49 pentacyclic triterpenoids and their glycosides, of plant and semisynthetic origin. Several of these compounds inhibited the multiplication of the yeast Saccharomyces carlsbergensis. The highest antifungal activity was found in the triterpene glycosides oleanolic acid and hederagenin, which have a free carboxyl group at C 28(27). Triterpenes of the meristotropic acid, macedonic acid, and lupan types had no fungistatic activity at concentrations up to 100 microgram/ml.

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Year:  1979        PMID: 549682

Source DB:  PubMed          Journal:  Biol Bull Acad Sci USSR        ISSN: 0098-2164


  1 in total

1.  Scalp Seborrheic Dermatitis and Dandruff Therapy Using a Herbal and Zinc Pyrithione-based Therapy of Shampoo and Scalp Lotion.

Authors:  Deganit Barak-Shinar; Lawrence J Green
Journal:  J Clin Aesthet Dermatol       Date:  2018-01-01
  1 in total

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