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Literature DB >> 5493859

Decreased ribonucleic acid synthesis in isolated rat liver nuclei during starvation.

Abstract

1. Isolated nuclei from starved rats showed a lowered incorporation of [(14)C]UMP into RNA. 2. The Mg(2+)-dependent incorporation was decreased by 30% after 1 day of starvation, but incorporation in the presence of Mn(2+) and ammonium sulphate decreased only after longer periods of starvation. 3. RNA synthesis by nuclei in the presence of excess of added RNA polymerase was unchanged after 1 day of starvation and was inhibited by 20% after 4 days. 4. The capacity of nuclei to bind actinomycin D was unchanged after 1 day and was decreased by 20% after 4 days of starvation.

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Year: 1970 PMID： 5493859 PMCID： PMC1179608 DOI： 10.1042/bj1200381

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

18 in total

1. Regulatory significance of transfer RNA charging levels. I. Measurements of charging levels in livers of chow-fed rats, fasting rats, and rats fed balanced or imbalanced mixtures of amino acids.

Authors: R E Allen; P L Raines; D M Regen
Journal: Biochim Biophys Acta Date: 1969-10-22

7. [Study of renewal of polysomal RNA, of transfer RNA and of "messenger" RNA in the liver of rats subjected to protein deficiency].

Authors: C Quirin-Stricker; P Mandel
Journal: Bull Soc Chim Biol (Paris) Date: 1968-03-02

8. The effect of prednisolone injected in vivo on RNA-polymerase activities in isolated rat thymus nuclei.

Authors: J Drews; L Wagner
Journal: Eur J Biochem Date: 1970-04

Review 9. Hormones and the synthesis and utilization of ribonucleic acids.

Authors: J R Tata
Journal: Prog Nucleic Acid Res Mol Biol Date: 1966

10. Studies on the pathogenesis of liver necrosis by alpha-amanitin. Effect of alpha-amanitin on ribonucleic acid synthesis and on ribonucleic acid polymerase in mouse liver nuclei.

Authors: F Stirpe; L Fiume
Journal: Biochem J Date: 1967-11 Impact factor: 3.857

10 in total

4. Methylation of newly synthesized ribonucleic acid by isolated rat liver nuclei. Characterization of the ribonucleic acid synthesized by nuclei from starved animals.

Authors: D Rickwood; H G Klemperer
Journal: Biochem J Date: 1971-08 Impact factor: 3.857

5. The effect of feeding on the apparent kinetic constants and activation energy of the magnesium ion-activated deoxyribonucleic acid-dependent ribonucleic acid polymerase of rat liver.

Authors: C A Spencer; A R Henderson
Journal: Biochem J Date: 1971-11 Impact factor: 3.857

9. Response of poly(adenylic acid) polymerase in rat liver nuclei and mitochondria to stravation and re-feeding with amino acids.

Authors: S T Jacob; K M Rose; H N Munro
Journal: Biochem J Date: 1976-08-15 Impact factor: 3.857

10. The stability of rat liver ribonucleic acid in vivo after methylation with methyl methanesulphonate or dimethylnitrosamine.

Authors: M J McElhone; P J O'Connor; A W Craig
Journal: Biochem J Date: 1971-12 Impact factor: 3.857

10 in total

Decreased ribonucleic acid synthesis in isolated rat liver nuclei during starvation.

1. Regulatory significance of transfer RNA charging levels. I. Measurements of charging levels in livers of chow-fed rats, fasting rats, and rats fed balanced or imbalanced mixtures of amino acids.

2. A procedure for the isolation of enzymically active rat-liver nuclei.

3. Alpha-amanitin: a specific inhibitor of one of two DNA-pendent RNA polymerase activities from calf thymus.

4. Actinomycin binding capacity of deoxyribonucleoprotein.

5. Control of RNA polymerase reactions in isolated nuclei and nucleoli.

6. Ribonucleic acid biosynthesis of human cells during amino acid deprivation.

7. [Study of renewal of polysomal RNA, of transfer RNA and of "messenger" RNA in the liver of rats subjected to protein deficiency].

8. The effect of prednisolone injected in vivo on RNA-polymerase activities in isolated rat thymus nuclei.

Review 9. Hormones and the synthesis and utilization of ribonucleic acids.

10. Studies on the pathogenesis of liver necrosis by alpha-amanitin. Effect of alpha-amanitin on ribonucleic acid synthesis and on ribonucleic acid polymerase in mouse liver nuclei.

1. Ribonucleic acid synthesis in the renal cortex at the initiation of compensatory growth.

2. Activity of some enzymes of nucleic acid metabolism in developing rat liver.

3. The influence of diet on ribonucleic acid polymerase activity.

4. Methylation of newly synthesized ribonucleic acid by isolated rat liver nuclei. Characterization of the ribonucleic acid synthesized by nuclei from starved animals.

5. The effect of feeding on the apparent kinetic constants and activation energy of the magnesium ion-activated deoxyribonucleic acid-dependent ribonucleic acid polymerase of rat liver.

6. The effect of starvation on the cholinesterase activity of the liver and serum of young male rats.

Review 7. L-Tryptophan action on hepatic RNA synthesis and enzyme induction.

8. Effect of tryptophan on rat hepatic nuclear poly(A)polymerase activity.

9. Response of poly(adenylic acid) polymerase in rat liver nuclei and mitochondria to stravation and re-feeding with amino acids.

10. The stability of rat liver ribonucleic acid in vivo after methylation with methyl methanesulphonate or dimethylnitrosamine.