Literature DB >> 5485725

Stability of antibiotics and chemotherapeutics in agar plates.

K J Ryan, G M Needham, C L Dunsmoor, J C Sherris.   

Abstract

The stability of chemotherapeutic agents incorporated into agar plates was studied by comparison of minimum inhibitory concentrations on fresh and stored plates and by direct bioassay of the chemotherapeutic agar plates. Plates were stored in sealed bags at 4 C. No loss of bioactivity was demonstrated after 30 days of storage in plates containing methicillin, erythromycin, cephalothin, tetracycline, chloramphenicol, kanamycin, streptomycin, polymyxin B, or nalidixic acid. Penicillin G, ampicillin, and nitrofurantoin showed statistically significant losses of activity after 4 weeks. None of the chemotherapeutics tested showed significant loss in activity after 1 week.

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Year:  1970        PMID： 5485725      PMCID： PMC376956          DOI： 10.1128/am.20.3.447-451.1970

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  2 in total

1.  Drug resistance as influenced by inactivated sensitivity discs.

Authors:  L J Griffith; C G Mullins
Journal:  Appl Microbiol       Date:  1968-04

2.  Simplified, accurate method for antibiotic assay of clinical specimens.

Authors:  J V Bennett; J L Brodie; E J Benner; W M Kirby
Journal:  Appl Microbiol       Date:  1966-03
  2 in total
  9 in total

1.  Stability of antimycobacterial drugs in susceptibility testing.

Authors:  M E Griffith; H L Bodily
Journal:  Antimicrob Agents Chemother       Date:  1992-11       Impact factor: 5.191

2.  Early detection and preliminary susceptibility testing of positive pediatric blood cultures with the Steers replicator.

Authors:  J W Paisley; J K Todd; M H Roe
Journal:  J Clin Microbiol       Date:  1977-10       Impact factor: 5.948

3.  Yersinia enterocolitica: in vitro antimicrobial susceptibility.

Authors:  M Raevuori; S M Harvey; M J Pickett; W J Martin
Journal:  Antimicrob Agents Chemother       Date:  1978-05       Impact factor: 5.191

4.  An Undergraduate Laboratory Exploring Mutational Mechanisms in Escherichia coli Based on the Luria-Delbrück Experiment.

Authors:  Elizabeth A Hutchison; Abigail Scheffler; Kevin T Militello; Josephine Reinhardt; Hristina Nedelkovska; Varuni K Jamburuthugoda
Journal:  J Microbiol Biol Educ       Date:  2022-03-14

5.  Agar disk elution method for susceptibility testing of Mycobacterium marinum and Mycobacterium fortuitum complex to sulfonamides and antibiotics.

Authors:  M S Stone; R J Wallace; J M Swenson; C Thornsberry; L A Christensen
Journal:  Antimicrob Agents Chemother       Date:  1983-10       Impact factor: 5.191

6.  Ampicillin killing curve patterns of Haemophilus influenzae type b isolates by agar dilution plate count method.

Authors:  B F Woolfrey; M E Gresser-Burns; R T Lally
Journal:  Antimicrob Agents Chemother       Date:  1987-11       Impact factor: 5.191

7.  Analysis of rifampin disk diffusion and stability in 7H10 agar.

Authors:  J R Bonalsky; D Jaconia; E A Konopka; F W Adair
Journal:  Antimicrob Agents Chemother       Date:  1975-08       Impact factor: 5.191

8.  Comparison of drug sensitivity testing with microdilution quantitative minimum inhibitory concentration and the Autobac I system.

Authors:  C V Jacob; J Kleineman
Journal:  J Clin Microbiol       Date:  1980-05       Impact factor: 5.948

9.  Study of the Aminoglycoside Subsistence Phenotype of Bacteria Residing in the Gut of Humans and Zoo Animals.

Authors:  Teresita de J Bello González; Tina Zuidema; Gerrit Bor; Hauke Smidt; Mark W J van Passel
Journal:  Front Microbiol       Date:  2016-01-11       Impact factor: 5.640
  9 in total

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