| Literature DB >> 5483322 |
J G Azzopardi, E Freeman, G Poole.
Abstract
In an unselected series of 185 patients with histologically confirmed bronchial carcinoma 16 had endocrine disturbances attributable to the tumour (excluding pulmonary osteoarthropathy). Of these, 11 patients had hypercalcaemia; three inappropriate secretion of antidiuretic hormone; one Cushing's disease; three hypertrophic osteoarthropathy; and one gynaecomastia. Cushing's disease and inappropriate antidiuresis are specifically associated with oat-cell tumours, and hypercalcaemia occurs most frequently with squamous carcinoma. A negative correlation exists between gynaecomastia and osteoarthropathy on the one hand and oat-cell carcinoma on the other.Entities:
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Year: 1970 PMID: 5483322 PMCID: PMC1820058 DOI: 10.1136/bmj.4.5734.528
Source DB: PubMed Journal: Br Med J ISSN: 0007-1447