Literature DB >> 548161

Pharmacological study of bovine airways. Evidence for excitatory and inhibitory effects of histamine.

N Chand, P Eyre, L DeRoth.   

Abstract

Bovine airway muscle contracts to carbachol greater than histamine greater than 2-methylhistamine greater than prostaglandin F2 alpha. Trachea of neonatal calves are more sensitive to histamine than those of older cattle. Partially contracted bovine airways relax to prostaglandins E1 and E2 greater than dopamine greater than phenylephrine greater than 4-methylhistamine greater than dimaprit. Histamine-induced airway constriction was incompletely blocked by mepyramine and the mepyramine-resistant component was blocked by atropine. After H1-receptor blockade, histamine-induced tracheobronchial relaxation was incompletely antagonized by metiamide and not blocked by propranolol or indomethacine, suggesting an atypical histamine receptor not associated with catecholamine or prostaglandin production.

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Year:  1979        PMID： 548161      PMCID： PMC1320010     

Source DB:  PubMed          Journal:  Can J Comp Med        ISSN： 0008-4050


  29 in total

1.  Quantitative studies of antagonists for 5-hydroxytryptamine.

Authors:  J H GADDUM; K A HAMEED; D E HATHWAY; F F STEPHENS
Journal:  Q J Exp Physiol Cogn Med Sci       Date:  1955-01

2.  alpha and beta-adrenoceptors in chicken airways.

Authors:  N Chand; P Eyre
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1978-02

3.  Histamine receptors of airway smooth muscle of ferret and rat.

Authors:  N Chand; P Eyre
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1978-07

4.  Tryptamine-induced drug effects insensitive to serotoninergic antagonists: evidence of specific tryptaminergic receptor stimulation?

Authors:  R M Quock; B G Weick
Journal:  J Pharm Pharmacol       Date:  1978-05       Impact factor: 3.765

5.  Atypical (relaxant) response to histamine in cat bronchus.

Authors:  N Chand; P Eyre
Journal:  Agents Actions       Date:  1977-07

6.  Acute systemic anaphylaxis in adult domestic fowl--possible role of vasoactive lipids and peptides.

Authors:  N Chand; P Eyre
Journal:  Arch Int Pharmacodyn Ther       Date:  1978-11

7.  Spasmolytic action of histamine in airway smooth muscle of horse.

Authors:  N Chand; P Eyre
Journal:  Agents Actions       Date:  1978-04

8.  Postnatal developmental changes in adrenergic receptor responses of the dog tracheal muscle.

Authors:  K H Pandya
Journal:  Arch Int Pharmacodyn Ther       Date:  1977-11

9.  Histamine modulation of eosinophil migration.

Authors:  R A Clark; J A Sandler; J I Gallin; A P Kaplan
Journal:  J Immunol       Date:  1977-01       Impact factor: 5.422

10.  Relaxant action of histamine on rabbit trachea: possible existence of third histamine receptor subtype.

Authors:  N Chand; P Eyre; L DeRoth
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1979-02
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  3 in total

1.  Oscillatory measurements, blood gas analysis and clinical observations after intravenous clenbuterol administration in healthy and acutely pneumonic calves.

Authors:  P Reinhold
Journal:  Vet Res Commun       Date:  1993       Impact factor: 2.459

2.  Effects of Pasteurella haemolytica culture supernate on bovine tracheal smooth muscle.

Authors:  A Bélanger; W H Harris; S Yamashiro
Journal:  Can J Vet Res       Date:  1993-07       Impact factor: 1.310

3.  The influence of clenbuterol on prostaglandin F2 alpha-induced dyspnoea in calves.

Authors:  J Nuytten; E Muylle; W Oyaert; C Van den Hende
Journal:  Vet Res Commun       Date:  1986-11       Impact factor: 2.459
  3 in total

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