Literature DB >> 548018

Alternative pathway activation of complement by a murine parasitic nematode (Nematospiroides dubius).

S J Prowse, P L Ey, C R Jenkin.   

Abstract

The cuticular surface of the infectious third-stage larvae of Nematospiroides dubius activates complement via the alternative pathway. Sensitisation of larvae with complement or with antibodies from the serum of immune mice (resistant to reinfection) promoted the adherence of mouse peritoneal exudate cells to the larval cuticle during incubation in vitro. The infectivity of larvae sensitized with antibody or complement was significantly reduced after incubation with cells from immune mice.

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Year:  1979        PMID: 548018     DOI: 10.1038/icb.1979.47

Source DB:  PubMed          Journal:  Aust J Exp Biol Med Sci        ISSN: 0004-945X


  4 in total

1.  Antibody-mediated trapping of helminth larvae requires CD11b and Fcγ receptor I.

Authors:  Julia Esser-von Bieren; Beatrice Volpe; Manuel Kulagin; Duncan B Sutherland; Romain Guiet; Arne Seitz; Benjamin J Marsland; J Sjef Verbeek; Nicola L Harris
Journal:  J Immunol       Date:  2014-12-29       Impact factor: 5.422

2.  Loss of complement activation and leukocyte adherence as Nippostrongylus brasiliensis develops within the murine host.

Authors:  Paul R Giacomin; Hui Wang; David L Gordon; Marina Botto; Lindsay A Dent
Journal:  Infect Immun       Date:  2005-11       Impact factor: 3.441

3.  Cellular response and resistance to the primary infection of rats and mice with Nematospiroides dubius.

Authors:  B Schmitz; P Possart-Schmitz; M Gehrung; U Stauffer; H Mossmann; H Fischer
Journal:  Z Parasitenkd       Date:  1982

Review 4.  The innate allergenicity of helminth parasites.

Authors:  Franco H Falcone; Alex Loukas; Rupert J Quinnell; David I Pritchard
Journal:  Clin Rev Allergy Immunol       Date:  2004-02       Impact factor: 8.667

  4 in total

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