| Literature DB >> 54795 |
Abstract
The beta effects of adrenergic stimulation are often diminished in asthmatics in whom the condition is active. Corticosteroids are thought to lower the threshold of beta-adrenergic receptors to the response of catecholamines. A single intravenous injection of 40 mg prednisolone appeared to restore responsiveness to inhaled isoprenaline in eight out of ten chronic asthmatics who were previously non-responsive to catecholamines.Entities:
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Year: 1975 PMID： 54795 DOI： 10.1016/s0140-6736(75)90608-x
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321