Literature DB >> 5472783

Antilymphocyte serum and tissue culture used to investigate role of cell-mediated response in viral encephalitis in mice.

G A Rook, H E Webb.   

Abstract

Antilymphocyte serum given to suppress selectively the cell response to Langat virus in Swiss albino mice prolonged the average survival times. In vitro, lymph-node cells from virus-immunized mice were strongly cytotoxic for syngenic non-neuronal brain cells infected with virus. The implications of these findings are discussed, with particular reference to the concept of autoimmunity.

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Year:  1970        PMID： 5472783      PMCID： PMC1819743          DOI： 10.1136/bmj.4.5729.210

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  13 in total

1.  Lysis of homologous cells by sensitized lymphocytes in tissue culture.

Authors:  W ROSENAU; H D MOON
Journal:  J Natl Cancer Inst       Date:  1961-08       Impact factor: 13.506

2.  Malignant changes in New Zealand black mice.

Authors:  J East; M A De Sousa; P R Prosser; H Jaquet
Journal:  Clin Exp Immunol       Date:  1967-07       Impact factor: 4.330

3.  Measles as an index of immunological function.

Authors:  F M Burnet
Journal:  Lancet       Date:  1968-09-14       Impact factor: 79.321

4.  Langat virus encephalitis in mice. II. The effect of irradiation.

Authors:  H E Webb; D G Wight; G Wiernik; G S Platt; C E Smith
Journal:  J Hyg (Lond)       Date:  1968-09

5.  Latent viruses in chimpanzees with experimental kuru.

Authors:  N G Rogers; M Basnight; C J Gibbs; D C Gajdusek
Journal:  Nature       Date:  1967-11-04       Impact factor: 49.962

Review 6.  Cell-mediated immune responses to virus infections and virus-induced tumours.

Authors:  A C Allison
Journal:  Br Med Bull       Date:  1967-01       Impact factor: 4.291

7.  Lymphocyte in vitro cytotoxicity: lymphotoxins of several mammalian species.

Authors:  T W Williams; G A Granger
Journal:  Nature       Date:  1968-09-07       Impact factor: 49.962

8.  The reaction of astrocytes to acute virus infections of the central nervous system.

Authors:  I Zlotnik
Journal:  Br J Exp Pathol       Date:  1968-12

9.  Cell to cell interaction in the immune response. IV. Site of action of antilymphocyte globulin.

Authors:  W J Martin; J F Miller
Journal:  J Exp Med       Date:  1968-10-01       Impact factor: 14.307

10.  Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. I. Characterization of the phenomenon.

Authors:  N H Ruddle; B H Waksman
Journal:  J Exp Med       Date:  1968-12-01       Impact factor: 14.307
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  5 in total

1.  Delayed-type hypersensitivity responses in mice infected with St. Louis encephalitis virus: kinetics of the response and effects of immunoregulatory agents.

Authors:  B W Hudson; K Wolff; J C DeMartini
Journal:  Infect Immun       Date:  1979-04       Impact factor: 3.441

2.  Dual role of the immune response in street rabiesvirus infection of mice.

Authors:  J S Smith; C L McCelland; F L Reid; G M Baer
Journal:  Infect Immun       Date:  1982-01       Impact factor: 3.441

3.  Zika virus infection of the central nervous system of mice.

Authors:  T M Bell; E J Field; H K Narang
Journal:  Arch Gesamte Virusforsch       Date:  1971

Review 4.  Can antiglycolipid antibodies present in HIV-infected individuals induce immune demyelination?

Authors:  S Petratos; M E Gonzales
Journal:  Neuropathology       Date:  2000-12       Impact factor: 1.906

5.  Can viral envelope glycolipids produce auto-immunity, with reference to the CNS and multiple sclerosis?

Authors:  H E Webb; J K Fazakerley
Journal:  Neuropathol Appl Neurobiol       Date:  1984 Jan-Feb       Impact factor: 8.090
  5 in total

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