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Literature DB >> 5470117

Development of vascular lesions in insulin-treated animals fed a normal diet.

Abstract

Experiments were undertaken to study the role of hyperinsulinism in the pathogenesis of atheroma. Chickens injected with long-acting insulin for 19 weeks developed lipid containing lesions in their aortas. This provides further evidence in favour of the hypothesis that insulin and atheroma are causally related.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Insulin

Year: 1970 PMID： 5470117 PMCID： PMC1701806 DOI： 10.1136/bmj.3.5724.685

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

10 in total

1. PLASMA-INSULIN CONCENTRATIONS AFTER MYOCARDIAL INFRACTION.

Authors: N PETERS; C N HALES
Journal: Lancet Date: 1965-05-29 Impact factor: 79.321

2. Effect of insulin in the induction and regression of atherosclerosis in the chick.

Authors: J STAMLER; R PICK; L N KATZ
Journal: Circ Res Date: 1960-05 Impact factor: 17.367

3. Insulin-stimulated lipogenesis in arterial tissue in relation to diabetes and atheroma.

Authors: R W Stout
Journal: Lancet Date: 1968-09-28 Impact factor: 79.321

4. Insulin and atheroma.

Authors: R W Stout; J Vallance-Owen
Journal: Lancet Date: 1969-05-31 Impact factor: 79.321

5. Insulin stimulation of cholesterol synthesis by arterial tissue.

Authors: R W Stout
Journal: Lancet Date: 1969-08-30 Impact factor: 79.321

6. Glucose tolerance, plasma lipids and serum insulin in patients with ischaemic heart diseases.

Authors: I Christiansen; T Deckert; K Kjerulf; K Midtgaard; H Worning
Journal: Acta Med Scand Date: 1968-10

7. Failure of insulin therapy to prevent cardiovascular lesions in diabetic rats fed an atherogenic diet.

Authors: R B Wilson; J M Martin; W S Hartroft
Journal: Diabetes Date: 1969-04 Impact factor: 9.461

8. Interrelationships of hyperinsulinism and hypertriglyceridemia in young patients with coronary heart disease.

Authors: M Tzagournis; R Chiles; J M Ryan; T G Skillman
Journal: Circulation Date: 1968-12 Impact factor: 29.690

9. [Glucose metabolism in fatty tissue and muscle of animals with metabolic obesity or obesity due to overeating].

Authors: W Stauffacher; B Jeanrenaud; A E Renold
Journal: Acta Clin Belg Date: 1968 Impact factor: 1.264

10. Plasma-insulin in coronary heart-disease: response to oral and intravenous glucose and to tolbutamide.

Authors: E A Nikkilä; T A Miettinen; M R Vesenne; R Pelkonen
Journal: Lancet Date: 1965-09-11 Impact factor: 79.321

10 in total

12 in total

7. [Plasma lipid pattern in diabetics before and after insulin treatment: total lipids, triglycerides, phospholipids, and -lipoprotein cholesterol and single NEFA (C 16 -C 18 )].

Authors: A M Bertolini; A Santagostino
Journal: Acta Diabetol Lat Date: 1972 May-Jun

Development of vascular lesions in insulin-treated animals fed a normal diet.

1. PLASMA-INSULIN CONCENTRATIONS AFTER MYOCARDIAL INFRACTION.

2. Effect of insulin in the induction and regression of atherosclerosis in the chick.

3. Insulin-stimulated lipogenesis in arterial tissue in relation to diabetes and atheroma.

4. Insulin and atheroma.

5. Insulin stimulation of cholesterol synthesis by arterial tissue.

6. Glucose tolerance, plasma lipids and serum insulin in patients with ischaemic heart diseases.

7. Failure of insulin therapy to prevent cardiovascular lesions in diabetic rats fed an atherogenic diet.

8. Interrelationships of hyperinsulinism and hypertriglyceridemia in young patients with coronary heart disease.

9. [Glucose metabolism in fatty tissue and muscle of animals with metabolic obesity or obesity due to overeating].

10. Plasma-insulin in coronary heart-disease: response to oral and intravenous glucose and to tolbutamide.

1. Some chemical indices of diabetic vascular disease.

2. Determination of total serum insulin (IRI) in insulin-treated diabetic patients.

3. [The prevention of diabetes].

4. The effect of insulin on the incorporation of sodium (1- 14 C)-acetate into the lipids of the rat aorta.

5. Role of hyperglycemia in the progression of diabetic vascular disease.

6. Diabetes and atherosclerosis--the role of insulin.

7. [Plasma lipid pattern in diabetics before and after insulin treatment: total lipids, triglycerides, phospholipids, and -lipoprotein cholesterol and single NEFA (C 16 -C 18 )].

Review 8. Hyperinsulinemia, hyperproinsulinemia and insulin resistance in the metabolic syndrome.

9. Insulin sensitivity in normotensive subjects during angiotensin converting enzyme inhibition with fosinopril.

10. Effect of insulin in the induction and regression of experimental cholesterol atherosclerosis in the rabbit.