Literature DB >> 5466135

Simple method of evaluating scrapie in mice.

K W Cochran, L B Allen.   

Abstract

Mice in advanced scrapie characteristically clasp their hindlegs together. As the disease progresses into the clasping stage, mice exhibit a sequence of identifiable hindleg reactions which have categorized and assigned relative scores permitting objective, quantitative evaluation of disease.

Entities:  

Mesh：

Year:  1970        PMID： 5466135      PMCID： PMC376869          DOI： 10.1128/am.20.1.72-74.1970

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  11 in total

1.  The clinical spectrum and early diagnosis of Dawson's encephalitis, with preliminary notes on treatment.

Authors:  J M Freeman
Journal:  J Pediatr       Date:  1969-10       Impact factor: 4.406

2.  Search for infectious etiology in chronic and subacute degenerative diseases of the central nervous system.

Authors:  C J Gibbs
Journal:  Curr Top Microbiol Immunol       Date:  1967       Impact factor: 4.291

3.  Brain damage and emotional behaviour: the effects of scrapie on the emotional responses of mice.

Authors:  R D Savage; E J Field
Journal:  Anim Behav       Date:  1965-10       Impact factor: 2.844

4.  The sequential development of the brain lesion of scrapie in three strains of mice.

Authors:  H Fraser; A G Dickinson
Journal:  J Comp Pathol       Date:  1968-07       Impact factor: 1.311

5.  Amantadine therapy in subacute sclerosing panencephalitis. A preliminary report.

Authors:  R H Haslam; M P McQuillen; D B Clark
Journal:  Neurology       Date:  1969-11       Impact factor: 9.910

6.  Metabolic modification of some neurologic disorders.

Authors:  G C Cotzias
Journal:  JAMA       Date:  1969-11-17       Impact factor: 56.272

7.  Relationships between chemical changes and histological damage in the brains of scrapie affected mice.

Authors:  D L Mould; M Dawson; J S Slater; I Zlotnik
Journal:  J Comp Pathol       Date:  1967-10       Impact factor: 1.311

8.  An assessment of the reliability of three methods used in evaluating the status of multiple sclerosis patients.

Authors:  J W Kuzma; N S Namerow; W W Tourtellotte; W A Sibley; J F Kurtzke; A S Rose; W J Dixon
Journal:  J Chronic Dis       Date:  1969-04

9.  Amantadine in the treatment of Parkinson's disease.

Authors:  R S Schwab; A C England; D C Poskanzer; R R Young
Journal:  JAMA       Date:  1969-05-19       Impact factor: 56.272

10.  Infection as the etiology of spongiform encephalopathy (Creutzfeldt-Jakob disease).

Authors:  C J Gibbs; D C Gajdusek
Journal:  Science       Date:  1969-09-05       Impact factor: 47.728
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