Literature DB >> 5465366

Absence of cystathionase in human fetal liver: is cystine essential?

J A Sturman, G Gaull, N C Raiha.   

Abstract

Cystathionase activity is not measurable in the livers of 24 human fetuses and 3 premature infants, and the concentration of cystathionine in the liver is higher than that of the brain. The placenta does not subserve the trans-sulfuration function. Cystine (or cysteine) thus may be an essential amino acid in the immature human.

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Year:  1970        PMID: 5465366     DOI: 10.1126/science.169.3940.74

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  38 in total

1.  Transcriptional control of amino acid homeostasis is disrupted in Huntington's disease.

Authors:  Juan I Sbodio; Solomon H Snyder; Bindu D Paul
Journal:  Proc Natl Acad Sci U S A       Date:  2016-07-19       Impact factor: 11.205

2.  Ascorbic acid prevents oxidative stress in glutathione-deficient mice: effects on lung type 2 cell lamellar bodies, lung surfactant, and skeletal muscle.

Authors:  A Jain; J Mårtensson; T Mehta; A N Krauss; P A Auld; A Meister
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-01       Impact factor: 11.205

3.  Plasma amino Acid concentrations in 108 children receiving a pediatric amino Acid formulation as part of parenteral nutrition.

Authors:  Chasity M Shelton; Amanda J Clark; Michael C Storm; Richard A Helms
Journal:  J Pediatr Pharmacol Ther       Date:  2010-04

4.  [The use of different cysteine derivatives in longterm parenteral nutrition].

Authors:  S Böhler; M Neuhäuser-Berthold
Journal:  Z Ernahrungswiss       Date:  1989-03

5.  Induction of cystathionase in human foetal liver.

Authors:  K Heinonen; N C Räihä
Journal:  Biochem J       Date:  1974-12       Impact factor: 3.857

6.  Thiol-Redox Regulation in Lung Development and Vascular Remodeling.

Authors:  Gaston Ofman; Trent E Tipple
Journal:  Antioxid Redox Signal       Date:  2019-03-04       Impact factor: 8.401

7.  Studies on cystathionase activity in rat liver and brain during development. Effects of hormones and amino acids in vivo.

Authors:  K Heinonen
Journal:  Biochem J       Date:  1973-12       Impact factor: 3.857

8.  [Total parenteral nutrition of premature infants: metabolic effects of an exogenous supply of L-aspartic acid and L-glutamic acid].

Authors:  P Jürgens; C Panteliadis; G Fondalinski
Journal:  Z Ernahrungswiss       Date:  1982-09

9.  [A cystine-containing short-chain peptide as a potential cystine source for parenteral nutrition].

Authors:  L Pollack; P Stehle; S Albers; P Fürst
Journal:  Z Ernahrungswiss       Date:  1989-09

10.  Regulation of glutathione metabolism in Ehrlich ascites tumour cells.

Authors:  J M Estrela; R Hernandez; P Terradez; M Asensi; I R Puertes; J Viña
Journal:  Biochem J       Date:  1992-08-15       Impact factor: 3.857

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