Literature DB >> 5464391

In vitro lymphocyte reactivity during depression of tuberculin hypersensitivity by 6-mercaptopurine.

B Zweiman, S M Phillips.   

Abstract

Administration of 6-mercaptopurine suppressed appearance of tuberculin skin test reactivity for up to 6 weeks after mycobacterial injection. Lymphocytes obtained during the period of suppressed tuberculin reactivity exhibited normal in vitro proliferative responses to tuberculin, suggesting that the drug may not be qualitatively affecting function of immunologically competent cells.

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Year:  1970        PMID： 5464391     DOI： 10.1126/science.169.3942.284

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

1.  Activity of various immunosuppressive drugs on tuberculin hypersensitivity reaction in chickens.

Authors:  I Karakoz; F Vosmík; B Blaszczyk; J Krejci; J Pekárek; T Hraba; K Hála
Journal:  Agents Actions       Date:  1977-07

2.  Effects of azathioprine therapy on bone marrow-dependent and thymus-dependent cells in man.

Authors:  N I Abdou; B Zweiman; S R Casella
Journal:  Clin Exp Immunol       Date:  1973-01       Impact factor: 4.330

Review 3.  Chemical markers of transplantation individuality solubilized with sonic energy.

Authors:  B D Kahan; R A Reisfeld
Journal:  Bacteriol Rev       Date:  1971-03

4.  Comparative study of cyclophosphamide, 6-mercaptopurine, azathiopurine and methotrexate. Relative effects on the humoral and the cellular immune response in the mouse.

Authors:  I G Otterness; Y H Chang
Journal:  Clin Exp Immunol       Date:  1976-11       Impact factor: 4.330

5.  Differential effects of immunosuppressants on lymphocyte function.

Authors:  A Winkelstein
Journal:  J Clin Invest       Date:  1973-09       Impact factor: 14.808
  5 in total

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