Literature DB >> 5462436

Blood concentrations of acetaldehyde and ethanol in chronic alcoholics.

E Majchrowicz, J H Mendelson.   

Abstract

Fifteen adult male alcoholic volunteers were studied before, during, and after a 10- to 15-day period of experimentally induced intoxication. Blood acetaldehyde concentrations ranged from 0.11 to 0.15 and from 0.04 to 0.08 milligrams per 100 milliliters when blood ethanol concentrations ranged from 1 to 400 milligrams per 100 milliliters after consumption of bourbon or grain ethanol, respectively. No dose or dose-time relationships were found between blood ethanol concentrations and blood acetaldehyde concentrations during any phase of this study.

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Year:  1970        PMID： 5462436     DOI： 10.1126/science.168.3935.1100

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  20 in total

1.  A longitudinal analysis of circulating stress-related proteins and chronic ethanol self-administration in cynomolgus macaques.

Authors:  Christa M Helms; Ilhem Messaoudi; Sophia Jeng; Willard M Freeman; Kent E Vrana; Kathleen A Grant
Journal:  Alcohol Clin Exp Res       Date:  2011-12-05       Impact factor: 3.455

2.  Voluntary ethanol consumption reduces GABAergic neuroactive steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) in the amygdala of the cynomolgus monkey.

Authors:  Matthew C Beattie; Antoniette M Maldonado-Devincci; Patrizia Porcu; Todd K O'Buckley; James B Daunais; Kathleen A Grant; A Leslie Morrow
Journal:  Addict Biol       Date:  2015-12-02       Impact factor: 4.280

3.  Voluntary ethanol intake predicts κ-opioid receptor supersensitivity and regionally distinct dopaminergic adaptations in macaques.

Authors:  Cody A Siciliano; Erin S Calipari; Verginia C Cuzon Carlson; Christa M Helms; David M Lovinger; Kathleen A Grant; Sara R Jones
Journal:  J Neurosci       Date:  2015-04-15       Impact factor: 6.167

4.  The effects of age at the onset of drinking to intoxication and chronic ethanol self-administration in male rhesus macaques.

Authors:  Christa M Helms; Andrew Rau; Jessica Shaw; Cara Stull; Steven W Gonzales; Kathleen A Grant
Journal:  Psychopharmacology (Berl)       Date:  2014-01-22       Impact factor: 4.530

5.  Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking.

Authors:  H Sprince; C M Parker; G G Smith; L J Gonzales
Journal:  Agents Actions       Date:  1975-05

6.  Ethanol, acetaldehyde, and myocardial protein synthesis.

Authors:  S S Schreiber; K Briden; M Oratz; M A Rothschild
Journal:  J Clin Invest       Date:  1972-11       Impact factor: 14.808

7.  Liquid-diet with alcohol alters maternal, fetal and placental weights and the expression of molecules involved in integrin signaling in the fetal cerebral cortex.

Authors:  Ujjwal K Rout; Julie M Dhossche
Journal:  Int J Environ Res Public Health       Date:  2010-11-17       Impact factor: 3.390

8.  Neuroactive Steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) and Pro-inflammatory Cytokine MCP-1 Levels in Hippocampus CA1 are Correlated with Voluntary Ethanol Consumption in Cynomolgus Monkey.

Authors:  Matthew C Beattie; Christopher S Reguyal; Patrizia Porcu; James B Daunais; Kathleen A Grant; A Leslie Morrow
Journal:  Alcohol Clin Exp Res       Date:  2017-12-05       Impact factor: 3.455

9.  Differential changes of blood and urinary indoleamines following intravenous ethanol administration in alcoholic and non-drinker women.

Authors:  C M Banki; M Vojnik
Journal:  J Neural Transm       Date:  1978       Impact factor: 3.575

10.  Effects of ethanol on axon outgrowth and branching in developing rat cortical neurons.

Authors:  E J Hoffman; C D Mintz; S Wang; D G McNickle; S R J Salton; D L Benson
Journal:  Neuroscience       Date:  2008-09-25       Impact factor: 3.590
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