| Literature DB >> 5456615 |
L Wetterberg, A Yuwiler, R Ulrich, E Geller, R Wallace.
Abstract
A circadian rhythm has been found in hydroxyindole-O-methyltransferase activity of the pineal gland of blinded 12-day-old rats. Five additional hours of lighting can partly prevent the nocturnal increase in pineal hydroxyindole-O-methyltransferase activity in such rats. Removal of the Harderian gland abolishes this response to light in 12-day-old blinded animals, giving further support to the suggestion that this gland may function as an extraretinal photosensitive organ influencing the pineal gland in blinded suckling rats.Entities:
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Year: 1970 PMID： 5456615 DOI： 10.1126/science.170.3954.194
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728