Literature DB >> 5451911

Binding and translation of turnip-yellow-mosaic-virus ribonucleic acid by skeletal-muscle ribosomes from normal and diabetic rats.

F S Rolleston, I G Wool, T E Martin.   

Abstract

Ribosomes from skeletal muscle of diabetic rats were less active than normal ribosomes in protein synthesis directed by turnip-yellow-mosaic-virus RNA. The proportion of ribosomes from muscle of diabetic rats capable of binding turnip-yellow-mosaic-virus RNA was greater than normal, but there was no difference in the equilibrium constants for the binding reaction. The turnip-yellow-mosaic-virus RNA was bound preferentially to the small (40S) ribosomal subunit, whereas the decrease due to diabetes in its translation was associated with the large (60S) subunit. Thus the diminished capacity of ribosomes from muscle of diabetic rats to translate turnip-yellow-mosaic-virus RNA was not the result of decreased binding of the template.

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Year:  1970        PMID： 5451911      PMCID： PMC1179048          DOI： 10.1042/bj1170899

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  12 in total

1.  Cell-free protein synthesis: the association of viral RNA and E. coli ribosomes.

Authors:  R HASELKORN; V A FRIED; J E DAHLBERG
Journal:  Proc Natl Acad Sci U S A       Date:  1963-04       Impact factor: 11.205

2.  The precision of ultraviolet absorption measurements in the Schmidt-Thannhauser procedure for nucleic acid estimation.

Authors:  A FLECK; H N MUNRO
Journal:  Biochim Biophys Acta       Date:  1962-05-14

3.  Insulin regulation of protein synthesis by muscle ribosomes: effect of the hormone on translation of messenger RNA for a regulatory protein.

Authors:  I G Wool; P Cavicchi
Journal:  Proc Natl Acad Sci U S A       Date:  1966-09       Impact factor: 11.205

4.  The relation of RNA and protein synthesis to the sedimentation of muscle ribosomes: effect of diabetes and insulin.

Authors:  W S Stirewalt; I G Wool; P Cavicchi
Journal:  Proc Natl Acad Sci U S A       Date:  1967-06       Impact factor: 11.205

Review 5.  Mode of action of insulin in the regulation of protein biosynthesis in muscle.

Authors:  I G Wool; W S Stirewalt; K Kurihara; R B Low; P Bailey; D Oyer
Journal:  Recent Prog Horm Res       Date:  1968

6.  The ribosome-binding sites in turnip yellow mosaic virus RNA.

Authors:  J E Dahlberg; R Haselkorn
Journal:  Proc Natl Acad Sci U S A       Date:  1966-05       Impact factor: 11.205

7.  Determination of the number of active muscle ribosomes: effect of diabetes and insulin.

Authors:  I G Wool; K Kurihara
Journal:  Proc Natl Acad Sci U S A       Date:  1967-12       Impact factor: 11.205

8.  Formation of active hybrids from subunits of muscle ribosomes from normal and diabetic rats.

Authors:  T E Martin; I G Wool
Journal:  Proc Natl Acad Sci U S A       Date:  1968-06       Impact factor: 11.205

9.  Studies on the genesis of polyribosomes. II. The association of nascent messenger RNA with the 40 S subribosomal particle.

Authors:  W K Joklik; Y Becker
Journal:  J Mol Biol       Date:  1965-09       Impact factor: 5.469

10.  On the significance of ribosome dimers in extracts of animal cells.

Authors:  R W Reader; C P Stanners
Journal:  J Mol Biol       Date:  1967-09-14       Impact factor: 5.469
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  2 in total

1.  In vitro synthesis of turnip yellow mosaic virus coat protein in a wheat germ cell-free system.

Authors:  C Benicourt; A L Haenni
Journal:  J Virol       Date:  1976-10       Impact factor: 5.103

2.  Aminoacyltransferase I-catalysed binding of phenylalanyl-transfer ribonucleic acid to muscle ribosomes from normal and diabetic rats.

Authors:  D P Leader; I G Wool; J J Castles
Journal:  Biochem J       Date:  1971-09       Impact factor: 3.857
  2 in total

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