Literature DB >> 5447531

Macroglobulin structure: variable sequence of light and heavy chains.

H Kohler, A Shimizu, C Paul, F W Putnam.   

Abstract

The variable regions of the light and heavy chains on the same macroglobulin (immunoglobulin M) molecule are no more related in amino acid sequence than are the variable regions of the light and heavy chains of different immunoglobulin molecules. Subgroups of micro chains are similar in their variable sequence to subgroups of gamma chains.

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Year:  1970        PMID： 5447531     DOI： 10.1126/science.169.3940.56

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Cold pepsin digestion: a novel method to produce the Fv fragment from human immunoglobulin M.

Authors:  L C Lin; F W Putnam
Journal:  Proc Natl Acad Sci U S A       Date:  1978-06       Impact factor: 11.205

2.  Amino-acid sequence of the variable region of the heavy (alpha) chain of a mouse myeloma protein with anti-hapten activity.

Authors:  S H Francis; R G Leslie; L Hood; H N Eisen
Journal:  Proc Natl Acad Sci U S A       Date:  1974-04       Impact factor: 11.205

Review 3.  Genetic determination of antibody specificity. Gene translocation and fusion, the molecular basis for the differentiation of the antibody-producing cell.

Authors:  N Hilschmann; H U Barnikol; H Kratzin; P Altevogt; M Engelhard; S Barnikol-Watanabe
Journal:  Naturwissenschaften       Date:  1978-12

4.  Amino acid sequence of the variable region of a human mu chain: location of a possible JH segment.

Authors:  D W Lehman; F W Putnam
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

5.  Light chain sequences of human IgM cold agglutinins (variable-region subgroups amino-acid sequence-kappa light chain-N-terminal).

Authors:  J D Capra; J M Kehoe; R C Williams; T Feizi; H G Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

6.  Interchain and intrachain disulfide bridges of a human immunoglobulin M: detection of a unique fragment.

Authors:  B Frangione; F Prelli; C Mihaesco; E C Franklin
Journal:  Proc Natl Acad Sci U S A       Date:  1971-07       Impact factor: 11.205
  6 in total

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