Literature DB >> 54445

In vitro viral transformation of human prostatic carcinoma.

R E Jones, E J Sanford, T J Rohner, F Rapp.   

Abstract

Cell cultures derived from fetal human and prostatic adenocarcinoma were inoculated with SV40 virus. Within 6 weeks in vitro morphologic transformation occurred, after which the cells proliferated rapidly. They exhibited the SV40 T-antigen by immunofluorescence and survived propagation beyond the limited lifespan of uninfected cultures. We suggest that this may be a useful technique in establishing stable cell lines of human prostate.

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Year:  1976        PMID: 54445     DOI: 10.1016/s0022-5347(17)59076-x

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  4 in total

1.  A virus-producing cell line developed by transformation of human parapharyngeal cells with SV40.

Authors:  K A Rafferty; R L Ruben; S K Young
Journal:  In Vitro       Date:  1978-02

Review 2.  Human cell transformation by simian virus 40--a review.

Authors:  G H Sack
Journal:  In Vitro       Date:  1981-01

3.  Isolation, in vitro cultivation, and electron microscopy of normal and malignant prostatic epithelial cells from the Copenhagen rat.

Authors:  F A Feuchter; D R Rowley; P M Heidger
Journal:  Urol Res       Date:  1980

4.  Transformation of human skeletal muscle cells by simian virus 40.

Authors:  A F Miranda; L E Babiss; P B Fisher
Journal:  Proc Natl Acad Sci U S A       Date:  1983-11       Impact factor: 11.205

  4 in total

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