Literature DB >> 5444264

Morphine: radioimmunoassay.

S Spector, C W Parker.   

Abstract

The development of a radioimmunoassay for morphine is described. The hapten morphine is made antigenic by coupling it to a protein at the phenolic group of the molecule. Extremely low concentrations of morphine (0.5 nanogram) can be measured by this assay procedure.

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Year:  1970        PMID： 5444264     DOI： 10.1126/science.168.3937.1347

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  29 in total

1.  Proceedings: The measurement of serum morphine levels by radioimmunoassay following oral administration of diamorphine or morphine.

Authors:  G W Aherne; V Marks; B A Morris; E M Piall; J D Robinson; R G Twycross
Journal:  Br J Pharmacol       Date:  1975-06       Impact factor: 8.739

2.  Amikacin: a rapid and sensitive radioimmunoassay.

Authors:  J E Lewis; J C Nelson; H A Elder
Journal:  Antimicrob Agents Chemother       Date:  1975-01       Impact factor: 5.191

3.  Antibodies as a means of isolating and characterizing biologically active substances: presence of a non-peptide, morphine-like compound in the central nervous system.

Authors:  A R Gintzler; A Levy; S Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1976-06       Impact factor: 11.205

4.  Binding of the endogenous nonpeptide morphine-like compound to opiate receptors.

Authors:  A J Blume; J Shorr; J P Finberg; S Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

5.  [Determination of morphine in the vitreous and cerebrospinal fluid by radioimmunoassay (author's transl)].

Authors:  J Bösche; H P Gelbke
Journal:  Z Rechtsmed       Date:  1977-04-18

Review 6.  Conjugate Vaccine Immunotherapy for Substance Use Disorder.

Authors:  Paul T Bremer; Kim D Janda
Journal:  Pharmacol Rev       Date:  2017-07       Impact factor: 25.468

7.  Effects of a morphine-rabbit anti-morphine antibody mixture on guinea-pig isolated ileum.

Authors:  M J Bleiberg; B W Janicki; W V Leahy
Journal:  Br J Pharmacol       Date:  1973-12       Impact factor: 8.739

8.  Coupling of a new, active morphine derivative to sepharose for affinity chromatography.

Authors:  E J Simon; W P Dole; J M Hiller
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

9.  Radioimmunological screening and gas chromatographic identification of diazepam in blood and serum.

Authors:  H P Gelbke; H J Schlicht; G Schmidt
Journal:  Arch Toxicol       Date:  1977-11-21       Impact factor: 5.153

10.  A rapid and sensitive assay for detection of nanogram quantities of castor-bean (Ricinus communis) lectins.

Authors:  M Ghosh; B K Bachhawat; A Surolia
Journal:  Biochem J       Date:  1979-10-01       Impact factor: 3.857
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