| Literature DB >> 5441687 |
L E D'Antonio, D T Spira, R C Fu, D M Dagnillo, P H Silverman.
Abstract
Plasmodium berghei were released from mouse erythrocytes by passage through a French pressure cell. The released organisms were washed and disintegrated; the soluble portion was chromatographed on a Sephadex (G-200) column. The void-volume eluate contained an erythrocyte-free plasmodial fraction which behaved as a vaccine, preventing parasitemia, anemia, and death in mice subsequently challenged with living Plasmodium berghei.Entities:
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Year: 1970 PMID： 5441687 DOI： 10.1126/science.168.3935.1117
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728