Literature DB >> 5441408

Gastrin derivatives investigated for secretory potency and for changes in gastric mucosal histamine formation.

E Rosengren, S E Svensson.   

Abstract

1. Acid secretion and rate of histamine formation in the gastric mucosa were determined in rats after injection of hog gastrin II, gastrin pentapeptide and some substituted analogues of the C-terminal tetrapeptide of gastrin.2. Accelerated mucosal histamine formation was induced by hog gastrin II, gastrin pentapeptide and those analogues which elicited acid secretion, whereas secretorily inactive derivatives did not alter histamine formation.

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Year:  1970        PMID： 5441408      PMCID： PMC1702565          DOI： 10.1111/j.1476-5381.1970.tb10589.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  8 in total

1.  THE CONSTITUTION AND PROPERTIES OF TWO GASTRINS EXTRACTED FROM HOG ANTRAL MUCOSA.

Authors:  R A GREGORY; H J TRACY
Journal:  Gut       Date:  1964-04       Impact factor: 23.059

2.  OBSERVATIONS ON THE INHIBITION OF HISTAMINE FORMATION.

Authors:  G KAHLSON; E ROSENGREN; R THUNBERG
Journal:  J Physiol       Date:  1963-12       Impact factor: 5.182

3.  MOBILIZATION AND FORMATION OF HISTAMINE IN THE GASTRIC MUCOSA AS RELATED TO ACID SECRETION.

Authors:  G KAHLSON; E ROSENGREN; D SVAHN; R THUNBERG
Journal:  J Physiol       Date:  1964-11       Impact factor: 5.182

4.  PHYSIOLOGICAL PROPERTIES OF A SERIES OF SYNTHETIC PEPTIDES STRUCTURALLY RELATED TO GASTRIN I.

Authors:  H J TRACY; R A GREGORY
Journal:  Nature       Date:  1964-12-05       Impact factor: 49.962

5.  Preparation of chronic denervated gastric pouches in the rat.

Authors:  R S ALPHIN; T M LIN
Journal:  Am J Physiol       Date:  1959-08

6.  Structure--function relationships in gastrin-like peptides.

Authors:  J S Morley
Journal:  Proc R Soc Lond B Biol Sci       Date:  1968-05-14

7.  The role of the antrum and the vagus nerve in the formation of gastric mucosal histamine.

Authors:  E Rosengren; S E Svensson
Journal:  J Physiol       Date:  1969-11       Impact factor: 5.182

8.  Structure-function relationships in the active C-terminal tetrapeptide sequence of gastrin.

Authors:  J S Morley; H J Tracy; R A Gregory
Journal:  Nature       Date:  1965-09-25       Impact factor: 49.962
  8 in total

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