Literature DB >> 5438052

Conversion of histidine to hercynine by Neurospora crassa.

V N Reinhold, Y Ishikawa, D B Melville.   

Abstract

Cell-free extracts of Neurospora crassa mycelium catalyze the methylation of l-histidine to form hercynine (histidine betaine). The partially methylated compounds, alpha-N-methyl-l-histidine and alpha-N,N-dimethyl-l-histidine, are also methylated by the same enzyme preparation to form hercynine. All three methylation reactions are stimulated by the addition of S-adenosylmethionine.

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Year:  1970        PMID： 5438052      PMCID： PMC250405          DOI： 10.1128/jb.101.3.881-884.1970

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  8 in total

1.  The reaction sequence in ergothioneine biosynthesis: hercynine as an intermediate.

Authors:  A ASKARI; D B MELVILLE
Journal:  J Biol Chem       Date:  1962-05       Impact factor: 5.157

2.  Transmethylation in the biosynthesis of ergothionelne.

Authors:  D B MELVILLE; M L LUDWIG; E INAMINE; J R RACHELE
Journal:  J Biol Chem       Date:  1959-05       Impact factor: 5.157

3.  The biosynthesis of ergothioneine.

Authors:  D B MELVILLE; S EICH; M L LUDWIG
Journal:  J Biol Chem       Date:  1957-02       Impact factor: 5.157

4.  Ergothioneine in microorganisms.

Authors:  D S GENGHOF; E INAMINE; V KOVALENKO; D B MELVILLE
Journal:  J Biol Chem       Date:  1956-11       Impact factor: 5.157

5.  Synthesis of alpha-N-methylated histidines.

Authors:  V N Reinhold; Y Ishikawa; D B Melville
Journal:  J Med Chem       Date:  1968-03       Impact factor: 7.446

6.  Properties of a phosphatidylmonomethylethanolamine N-methyl-transferase from Neurospora crassa.

Authors:  G A Scarborough; J F Nyc
Journal:  Biochim Biophys Acta       Date:  1967-09-12

7.  Biosynthesis of ergothioneine from endogenous hercynine in Mycobacterium smegmatis.

Authors:  D S Genghof; O Van Damme
Journal:  J Bacteriol       Date:  1968-02       Impact factor: 3.490

8.  BIOSYNTHESIS OF ERGOTHIONEINE AND HERCYNINE BY MYCOBACTERIA.

Authors:  D S GENGHOF; O VANDAMME
Journal:  J Bacteriol       Date:  1964-04       Impact factor: 3.490
  8 in total
  8 in total

1.  Biosynthesis of ergothioneine and hercynine by fungi and Actinomycetales.

Authors:  D S Genghof
Journal:  J Bacteriol       Date:  1970-08       Impact factor: 3.490

Review 2.  Ergothioneine, Ovothiol A, and Selenoneine-Histidine-Derived, Biologically Significant, Trace Global Alkaloids.

Authors:  Geoffrey A Cordell; Sujeewa N S Lamahewage
Journal:  Molecules       Date:  2022-04-21       Impact factor: 4.927

3.  Use of a Tyrosine Analogue To Modulate the Two Activities of a Nonheme Iron Enzyme OvoA in Ovothiol Biosynthesis, Cysteine Oxidation versus Oxidative C-S Bond Formation.

Authors:  Li Chen; Nathchar Naowarojna; Heng Song; Shu Wang; Jiangyun Wang; Zixin Deng; Changming Zhao; Pinghua Liu
Journal:  J Am Chem Soc       Date:  2018-03-21       Impact factor: 15.419

4.  Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity.

Authors:  Melissa Richard-Greenblatt; Horacio Bach; John Adamson; Sandra Peña-Diaz; Wu Li; Adrie J C Steyn; Yossef Av-Gay
Journal:  J Biol Chem       Date:  2015-07-30       Impact factor: 5.157

Review 5.  Mini-Review: Ergothioneine and Ovothiol Biosyntheses, an Unprecedented Trans-Sulfur Strategy in Natural Product Biosynthesis.

Authors:  Nathchar Naowarojna; Ronghai Cheng; Li Chen; Melissa Quill; Meiling Xu; Changming Zhao; Pinghua Liu
Journal:  Biochemistry       Date:  2018-04-06       Impact factor: 3.162

6.  Carnitine biosynthesis in Neurospora crassa: enzymatic conversion of lysine to epsilon-N-trimethyllysine.

Authors:  C J Rebouche; H P Broquist
Journal:  J Bacteriol       Date:  1976-06       Impact factor: 3.490

7.  Mechanistic studies of a novel C-S lyase in ergothioneine biosynthesis: the involvement of a sulfenic acid intermediate.

Authors:  Heng Song; Wen Hu; Nathchar Naowarojna; Ampon Sae Her; Shu Wang; Rushil Desai; Li Qin; Xiaoping Chen; Pinghua Liu
Journal:  Sci Rep       Date:  2015-07-07       Impact factor: 4.379

8.  The biology of ergothioneine, an antioxidant nutraceutical.

Authors:  Irina Borodina; Louise C Kenny; Cathal M McCarthy; Kalaivani Paramasivan; Etheresia Pretorius; Timothy J Roberts; Steven A van der Hoek; Douglas B Kell
Journal:  Nutr Res Rev       Date:  2020-02-13       Impact factor: 7.800
  8 in total

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