Literature DB >> 5436594

Human glomerular basement membrane: chemical alteration in diabetes mellitus.

P G Beisswenger, R G Spiro.   

Abstract

The human glomerular basement membrane belongs to the collagen family of proteins. It contains about 7 percent carbohydrate, half of which occurs as glucosylgalactose disaccharide units linked to hydroxylysine. Glomeruli from diabetics contain increased amounts of basement membrane material. In addition, these membranes show a distict chemical alteration c haracterized by a significant decrease in lysine, accoumpanied by an equivalent increase in hydroxylysine and hydroxylysine-linked disaccharide units.

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Year:  1970        PMID： 5436594     DOI： 10.1126/science.168.3931.596

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  36 in total

1.  Renal glucose utilization in genetically diabetic microangiopathy.

Authors:  M Chen; C Velasco; R A Camerini-Davalos
Journal:  Experientia       Date:  1975-10-15

Review 2.  Basement membrane.

Authors:  J T Ireland
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1978

Review 3.  Diseases of the collagen molecule.

Authors:  C I Levene
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1978

Review 4.  [Diabetic angiopathy].

Authors:  K Lundbaek
Journal:  Acta Diabetol Lat       Date:  1973 Mar-Apr

5.  [Isolation of soluble glycoproteins form the basement membrane of the human glomerulus using collagenase].

Authors:  P Bardos; M Lanson; J P Muh; P Degand
Journal:  Experientia       Date:  1974-08-15

6.  Alteration in the distribution of type IV collagen in glomerular basal laminae in diabetic rats as revealed by immunocytochemistry and morphometrical approach.

Authors:  M Bendayan
Journal:  Diabetologia       Date:  1985-06       Impact factor: 10.122

7.  Red cell age-related changes of hemoglobins AIa+b and AIc in normal and diabetic subjects.

Authors:  J F Fitzgibbons; R D Koler; R T Jones
Journal:  J Clin Invest       Date:  1976-10       Impact factor: 14.808

Review 8.  Diabetic glomerulosclerosis: current status.

Authors:  N Kalant
Journal:  Can Med Assoc J       Date:  1978-07-22       Impact factor: 8.262

9.  Electron microscopic observation of gastric mucosal capillaries in diabetics--relationship between diabetic microangiopathy and complications following gastrectomy.

Authors:  S Kihara; K Mori; M Akagi
Journal:  Gastroenterol Jpn       Date:  1983-06

Review 10.  Search for a biochemical basis of diabetic microangiopathy.

Authors:  R G Spiro
Journal:  Diabetologia       Date:  1976-03       Impact factor: 10.122
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