Literature DB >> 5435895

1,3-Bis(p-chlorobenzylideneamino)guanidine hydrochloride (robenzidene): new poultry anticoccidial agent.

S Kantor, R L Kennett, E Waletzky, A S Tomcufcik.   

Abstract

At 66 parts per million in the feed, robenzidene is highly effective in preventing chicken coccidiosis caused by any one of eight Eimeria species. Three times this dose is safe for broiler chickens. In dogs and rats, the toxicity was relatively low over a period of 90 days. In laboratory trials, the drug completely prevents oocyst production by seven species and greatly reduces oocyst production by Eimeria maxima.

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Year:  1970        PMID： 5435895     DOI： 10.1126/science.168.3929.373

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Induction signals for vancomycin resistance encoded by the vanA gene cluster in Enterococcus faecium.

Authors:  M H Lai; D R Kirsch
Journal:  Antimicrob Agents Chemother       Date:  1996-07       Impact factor: 5.191

2.  The antibiotic robenidine exhibits guanabenz-like cytoprotective properties by a mechanism independent of protein phosphatase PP1:PPP1R15A.

Authors:  Zander Claes; Marloes Jonkhout; Ana Crespillo-Casado; Mathieu Bollen
Journal:  J Biol Chem       Date:  2019-07-23       Impact factor: 5.157

3.  Studies on the mode of action of the coccidiostat robenidene.

Authors:  J F Ryley; R G Wilson
Journal:  Z Parasitenkd       Date:  1971

4.  In vitro Antibacterial Activity of Isopropoxy Benzene Guanidine Against Multidrug-Resistant Enterococci.

Authors:  Xiufeng Zhang; Dongdong Han; Pengfei Pei; Jie Hao; Yixing Lu; Peng Wan; Xianfeng Peng; Weibiao Lv; Wenguang Xiong; Zhenling Zeng
Journal:  Infect Drug Resist       Date:  2019-12-23       Impact factor: 4.003

5.  Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent.

Authors:  Abiodun D Ogunniyi; Manouchehr Khazandi; Andrew J Stevens; Sarah K Sims; Stephen W Page; Sanjay Garg; Henrietta Venter; Andrew Powell; Karen White; Kiro R Petrovski; Geraldine Laven-Law; Eliane G Tótoli; Hérida R Salgado; Hongfei Pi; Geoffrey W Coombs; Dean L Shinabarger; John D Turnidge; James C Paton; Adam McCluskey; Darren J Trott
Journal:  PLoS One       Date:  2017-09-05       Impact factor: 3.240

6.  Aminoguanidines: New leads for treatment of Giardia duodenalis infection.

Authors:  Rebecca J Abraham; Sam Abraham; Andrew J Stevens; Stephen W Page; Adam McCluskey; Darren J Trott; Ryan M O'Handley
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2019-04-08       Impact factor: 4.077

7.  Robenidine Analogues Are Potent Antimalarials in Drug-Resistant Plasmodium falciparum.

Authors:  Alina Krollenbrock; Yuexin Li; Jane Xu Kelly; Michael K Riscoe
Journal:  ACS Infect Dis       Date:  2021-03-16       Impact factor: 5.084
  7 in total

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