Literature DB >> 5428044

Abnormal metabolism of secondary bile acids in patients with cirrhosis.

Z R Vlahcevic, I Buhac, C C Bell, L Swell.   

Abstract

The composition of bile acids in human bile was determined in bile-rich duodenal fluid on four consecutive days in a group of seven patients with cirrhosis and eight control patients with no liver disease. There was a marked reduction of secondary biliary bile acids in cirrhotic patients. Possible mechanisms for these changes are discussed.

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Year:  1970        PMID: 5428044      PMCID: PMC1411544          DOI: 10.1136/gut.11.5.420

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  6 in total

1.  The effect of oral neomycin on the conversion of cholic acid to deoxycholic in man.

Authors:  J G HAMILTON
Journal:  Arch Biochem Biophys       Date:  1963-04       Impact factor: 4.013

2.  A simple method for the isolation and purification of total lipides from animal tissues.

Authors:  J FOLCH; M LEES; G H SLOANE STANLEY
Journal:  J Biol Chem       Date:  1957-05       Impact factor: 5.157

3.  Turnover and nature of fecal bile acids in germfree and infected rats fed cholic acid-24-14C; bile acids and steroids 41.

Authors:  B E GUSTAFSSON; S BERGSTROM; S LINDSTEDT; A NORMAN
Journal:  Proc Soc Exp Biol Med       Date:  1957-03

4.  Metabolism of desoxycholic acid in the rabbit. Bile acids and steroids, 28.

Authors:  P H EKDAHL; J SJOVALL
Journal:  Acta Physiol Scand       Date:  1955-10-27

5.  Degradation of bile salts by human intestinal bacteria.

Authors:  M J Hill; B S Drasar
Journal:  Gut       Date:  1968-02       Impact factor: 23.059

6.  On the conjugation and formation of bile acids in the human liver. I. On the excretion of bile acids by patients with postoperative choledochostomy drainage; bile acids and steroids 61.

Authors:  P H EKDAHL; J SJOVALL
Journal:  Acta Chir Scand       Date:  1958-05-10
  6 in total
  19 in total

1.  Linkage of gut microbiome with cognition in hepatic encephalopathy.

Authors:  Jasmohan S Bajaj; Jason M Ridlon; Phillip B Hylemon; Leroy R Thacker; Douglas M Heuman; Sean Smith; Masoumeh Sikaroodi; Patrick M Gillevet
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2011-09-22       Impact factor: 4.052

Review 2.  The role of microbiota in hepatic encephalopathy.

Authors:  Jasmohan S Bajaj
Journal:  Gut Microbes       Date:  2014-04-01

Review 3.  Altered Microbiome in Patients With Cirrhosis and Complications.

Authors:  Chathur Acharya; Jasmohan S Bajaj
Journal:  Clin Gastroenterol Hepatol       Date:  2018-08-09       Impact factor: 11.382

4.  Studies on biliary bile acid metabolism in hepato-biliary diseases.

Authors:  T Harada
Journal:  Gastroenterol Jpn       Date:  1975

5.  Relative concentrations of individual nonsulfated bile acids in the serum and bile of patients with cirrhosis.

Authors:  J E Struthers; S J Mehta; M D Kaye; J L Naylor
Journal:  Am J Dig Dis       Date:  1977-10

6.  Serum Bile Acids Are Associated with Pathological Progression of Hepatitis B-Induced Cirrhosis.

Authors:  Xiaoning Wang; Guoxiang Xie; Aihua Zhao; Xiaojiao Zheng; Fengjie Huang; Yixing Wang; Chun Yao; Wei Jia; Ping Liu
Journal:  J Proteome Res       Date:  2016-03-22       Impact factor: 4.466

7.  Usefulness of Simplified Nutritional Appetite Questionnaire (SNAQ) in Appetite Assessment in Elder Patients with Liver Cirrhosis.

Authors:  T Wang; J Shen
Journal:  J Nutr Health Aging       Date:  2018       Impact factor: 4.075

8.  Biliary lipids, faecal steroids, and liver function in patients with chronic active hepatitis and primary biliary cirrhosis: significance of hepatic orcein-stained complexes.

Authors:  Y A Kesäniemi; T A Miettinen; M P Salaspuro
Journal:  Gut       Date:  1981-07       Impact factor: 23.059

9.  Modulation of the fecal bile acid profile by gut microbiota in cirrhosis.

Authors:  Genta Kakiyama; William M Pandak; Patrick M Gillevet; Phillip B Hylemon; Douglas M Heuman; Kalyani Daita; Hajime Takei; Akina Muto; Hiroshi Nittono; Jason M Ridlon; Melanie B White; Nicole A Noble; Pamela Monteith; Michael Fuchs; Leroy R Thacker; Masoumeh Sikaroodi; Jasmohan S Bajaj
Journal:  J Hepatol       Date:  2013-01-16       Impact factor: 25.083

10.  Cholic acid synthesis as an index of the severity of liver disease in man.

Authors:  W C McCormick; C C Bell; L Swell; Z R Vlahcevic
Journal:  Gut       Date:  1973-11       Impact factor: 23.059

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