Literature DB >> 5427358

Brain adenosine triphosphate: decreased concentration precedes convulsions.

A P Sanders, R S Kramer, B Woodhall, W D Currie.   

Abstract

The concentration of adenosine triphosphate in the brain decreased before the onset of generalized convulsions in unanesthetized rats subjected to acute hypoxia or treated with hydroxylamine or pentylenetetrazole (Metrazol). As the convulsive episode continued, adenosine triphosphate decreased further. Stimulation of adenosine triphosphate production forestalled its disappearance from the brain and delayed the development of seizure activity.

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Year:  1970        PMID： 5427358     DOI： 10.1126/science.169.3941.206

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  4 in total

1.  Lithium protection against oxygen toxicity in rats: ammonia and amino acid metabolism.

Authors:  E W Banister; N M Bhakthan; A K Singh
Journal:  J Physiol       Date:  1976-09       Impact factor: 5.182

2.  The activity of erythrocyte and brain Na+/K+ and Mg2+-ATPases in rats subjected to acute homocysteine and homocysteine thiolactone administration.

Authors:  Aleksandra Rasić-Marković; Olivera Stanojlović; Dragan Hrncić; Danijela Krstić; Mirjana Colović; Veselinka Susić; Tatjana Radosavljević; Dragan Djuric
Journal:  Mol Cell Biochem       Date:  2009-02-18       Impact factor: 3.396

3.  Ultrastructural study of methionine sulfoximine-induced Alzheimer type II astrocytosis.

Authors:  J A Gutierrez; M D Norenberg
Journal:  Am J Pathol       Date:  1977-02       Impact factor: 4.307

Review 4.  Metabolic and Homeostatic Changes in Seizures and Acquired Epilepsy-Mitochondria, Calcium Dynamics and Reactive Oxygen Species.

Authors:  Stjepana Kovac; Albena T Dinkova Kostova; Alexander M Herrmann; Nico Melzer; Sven G Meuth; Ali Gorji
Journal:  Int J Mol Sci       Date:  2017-09-08       Impact factor: 5.923
  4 in total

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