Literature DB >> 5427353

Homozygous Hb J Tongariki: evidence for only one alpha chain structural locus in Melanesians.

R K Abramson, D L Rucknagel, D C Shreffler, J J Saave.   

Abstract

A high frequency of Hb J Tongariki (alpha 115 Ala --> Asp) was found in a Kilenge village in New Britain. Heterozygotes had 45 to 50 percent of the Hb J component (determined by cellulose acetate electrophoresis). Two homozygotes for Hb J had no Hb A, suggesting that in this family only one Hbalpha structural locus is present.

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Year:  1970        PMID： 5427353     DOI： 10.1126/science.169.3941.194

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

1.  Hemoglobin Koya Dora: high frequency of a chain termination mutant.

Authors:  W W De Jong; P Meera Khan; L F Bernini
Journal:  Am J Hum Genet       Date:  1975-01       Impact factor: 11.025

2.  Trimodality in the proportion of hemoglobin G Philadelphia in heterozygotes: evidence for heterogeneity in the number of human alpha chain loci.

Authors:  R M Baine; D L Rucknagel; P A Dublin; J G Adams
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

3.  Extremely high frequencies of alpha-globin gene deletion in Madang and on Kar Kar Island, Papua New Guinea.

Authors:  P T Yenchitsomanus; K M Summers; K K Bhatia; J Cattani; P G Board
Journal:  Am J Hum Genet       Date:  1985-07       Impact factor: 11.025

4.  Editorial: Multiple loci for human globin genes.

Authors:  E Schwartz
Journal:  Am J Hum Genet       Date:  1976-07       Impact factor: 11.025

Review 5.  [Genetic aspects of metabolic disorders].

Authors:  W Fuhrmann
Journal:  Klin Wochenschr       Date:  1971-05

6.  Thalassaemia in Cyprus.

Authors:  T Ashiotis; Z Zachariadis; K Sofroniadou; D Loukopoulos; G Stamatoyannopoulos
Journal:  Br Med J       Date:  1973-04-07

7.  Alpha-thalassemia in Papua New Guinea.

Authors:  P Yenchitsomanus; K M Summers; P G Board; K K Bhatia; G L Jones; K Johnston; G T Nurse
Journal:  Hum Genet       Date:  1986-12       Impact factor: 4.132

8.  Proportion of hemoglobin G Philadelphia (alpha 268 Asn leads to Lys beta 2) in heterozygotes is determined by alpha-globin gene deletions.

Authors:  G B Sancar; B Tatsis; M M Cedeno; R F Rieder
Journal:  Proc Natl Acad Sci U S A       Date:  1980-11       Impact factor: 11.205

9.  Variation in the number of genes coding for salivary amylase in the bank vole, clethrionomys glareola.

Authors:  J T Nielsen
Journal:  Genetics       Date:  1977-01       Impact factor: 4.562

Review 10.  Why are some genetic diseases common? Distinguishing selection from other processes by molecular analysis of globin gene variants.

Authors:  J Flint; R M Harding; J B Clegg; A J Boyce
Journal:  Hum Genet       Date:  1993-03       Impact factor: 4.132
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