Literature DB >> 5417085

Lincomycin. X. The chemical synthesis of lincomycin.

B J Magerlein.   

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Year:  1970        PMID： 5417085     DOI： 10.1016/s0040-4039(01)87558-4

Source DB:  PubMed          Journal:  Tetrahedron Lett        ISSN： 0040-4039            Impact factor:   2.415


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  6 in total

1.  Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA.

Authors:  Yoshinari Wakiyama; Ko Kumura; Eijiro Umemura; Satomi Masaki; Kazutaka Ueda; Takashi Watanabe; Mikio Yamamoto; Yoko Hirai; Keiichi Ajito
Journal:  J Antibiot (Tokyo)       Date:  2015-12-16       Impact factor: 2.649

2.  Synthesis and SARs of novel lincomycin derivatives Part 5: optimization of lincomycin analogs exhibiting potent antibacterial activities by chemical modification at the 6- and 7-positions.

Authors:  Yoshinari Wakiyama; Ko Kumura; Eijiro Umemura; Satomi Masaki; Kazutaka Ueda; Yasuo Sato; Yoko Hirai; Yoshio Hayashi; Keiichi Ajito
Journal:  J Antibiot (Tokyo)       Date:  2017-11-01       Impact factor: 2.649

3.  Synthesis and structure-activity relationships of novel lincomycin derivatives part 3: discovery of the 4-(pyrimidin-5-yl)phenyl group in synthesis of 7(S)-thiolincomycin analogs.

Authors:  Yoshinari Wakiyama; Ko Kumura; Eijiro Umemura; Satomi Masaki; Kazutaka Ueda; Yasuo Sato; Takashi Watanabe; Yoko Hirai; Keiichi Ajito
Journal:  J Antibiot (Tokyo)       Date:  2016-10-05       Impact factor: 2.649

4.  Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities.

Authors:  Yoshinari Wakiyama; Ko Kumura; Eijiro Umemura; Kazutaka Ueda; Takashi Watanabe; Keiko Yamada; Takafumi Okutomi; Keiichi Ajito
Journal:  J Antibiot (Tokyo)       Date:  2017-05-31       Impact factor: 2.649

Review 5.  The evolving role of chemical synthesis in antibacterial drug discovery.

Authors:  Peter M Wright; Ian B Seiple; Andrew G Myers
Journal:  Angew Chem Int Ed Engl       Date:  2014-07-02       Impact factor: 15.336

6.  Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification.

Authors:  Yoshinari Wakiyama; Ko Kumura; Eijiro Umemura; Kazutaka Ueda; Satomi Masaki; Megumi Kumura; Hideki Fushimi; Keiichi Ajito
Journal:  J Antibiot (Tokyo)       Date:  2015-12-16       Impact factor: 2.649
  6 in total

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