Literature DB >> 5416535

Spontaneous rhythmic contraction of separated heart muscle cells.

S Bloom.   

Abstract

Muscle cells that conitract spontaneously and rhythmically can be obtained from adult mouse myocardium. Contractions are observed immediately after homogenization in a solution that is ionically similar to intracellular fluid. Contraction frequency varies directly with temperature and decreases as a function of time after homogenization. At 16 degrees C rhythmic relaxation and contraction occur for about 20 minutes. Contractions are dependent on the presence of adenosine triphosphate in the homogenization medium.

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Year:  1970        PMID： 5416535     DOI： 10.1126/science.167.3926.1727

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  7 in total

1.  Spontaneous tension oscillations in guinea-pig atrial trabeculae.

Authors:  H G Glitsch; L Pott
Journal:  Pflugers Arch       Date:  1975-07-09       Impact factor: 3.657

2.  Separation of beating cardiac myocytes from suspensions of heart cells.

Authors:  T G Pretlow; M R Glick; W J Reddy
Journal:  Am J Pathol       Date:  1972-05       Impact factor: 4.307

3.  The adrenergically mediated coordination of contraction in isolated cell groups from rat ventricular myocardium.

Authors:  K Pelkonen; R Tirri
Journal:  Experientia       Date:  1972-09-15

4.  Isometric force development, isotonic shortening, and elasticity measurements from Ca2+-activated ventricular muscle of the guinea pig.

Authors:  D W Maughan; E S Low; N R Alpert
Journal:  J Gen Physiol       Date:  1978-04       Impact factor: 4.086

5.  Force velocity relations of single cardiac muscle cells: calcium dependency.

Authors:  N M De Clerck; V A Claes; D L Brutsaert
Journal:  J Gen Physiol       Date:  1977-02       Impact factor: 4.086

6.  Myoplasmic free calcium concentration reached during the twitch of an intact isolated cardiac cell and during calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned cardiac cell from the adult rat or rabbit ventricle.

Authors:  A Fabiato
Journal:  J Gen Physiol       Date:  1981-11       Impact factor: 4.086

7.  Spontaneous mechanical activity in depolarized frog ventricle.

Authors:  S Winegrad
Journal:  J Gen Physiol       Date:  1976-08       Impact factor: 4.086
  7 in total

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