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Literature DB >> 5415286

Bone marrow and spleen: dissociation of immunologic properties by cortisone.

Abstract

Bone marrow and spleen cells react differently after treatment with cortisone acetate in vivo. Antibody-forming, hematopoietic, and proliferative responses of spleen cells are reduced, while bone marrow cell responses are not. The stimulation of spleen cells by phytohemagglutinin is abolished, but the response of marrow cells is enhanced. These reactions provide functional markers for the different cells involved in immunologic responses.

Entities: Chemical

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Year: 1970 PMID： 5415286 DOI： 10.1126/science.167.3924.1515

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

31 in total

1. The influence of prednisolone on the recirculation of peripheral blood lymphocytes in vivo.

Authors: E Bloemena; S Weinreich; P T Schellekens
Journal: Clin Exp Immunol Date: 1990-06 Impact factor: 4.330

2. High levels of free fatty acids and their esters in lymphoid cells resistant to cortisone or cyclophosphamide.

Authors: S Kigoshi; M Akiyama
Journal: Experientia Date: 1976

3. Antigenic competition between horse and sheep red blood cells as a hormone-dependent phenomenon.

Authors: H O Besedovsky; A Del Rey; E Sorkin
Journal: Clin Exp Immunol Date: 1979-07 Impact factor: 4.330

4. Immunologic and genetic factors influencing reproduction. A review.

Authors: T J Gill; C F Repetti
Journal: Am J Pathol Date: 1979-05 Impact factor: 4.307

5. Lack of correlation between the effects of cortisone on mouse spleen plaque-forming cells and circulating anti-sheep red blood cell haemolysins.

Authors: A Ferreira; C Moreno; G Hoecker
Journal: Immunology Date: 1973-04 Impact factor: 7.397

10. Effects of corticosteroids on immunity in man. I. Decreased serum IgG concentration caused by 3 or 5 days of high doses of methylprednisolone.

Authors: W T Butler; R D Rossen
Journal: J Clin Invest Date: 1973-10 Impact factor: 14.808

Bone marrow and spleen: dissociation of immunologic properties by cortisone.

1. The influence of prednisolone on the recirculation of peripheral blood lymphocytes in vivo.

2. High levels of free fatty acids and their esters in lymphoid cells resistant to cortisone or cyclophosphamide.

3. Antigenic competition between horse and sheep red blood cells as a hormone-dependent phenomenon.

4. Immunologic and genetic factors influencing reproduction. A review.

5. Lack of correlation between the effects of cortisone on mouse spleen plaque-forming cells and circulating anti-sheep red blood cell haemolysins.

6. Reactivity of RA and SLE lymphocytes stimulated by anti-Ig antibodies.

Review 7. [Development of the immune system (author's transl)].

8. Perforin mRNA expression in the inflamed tissues of NZB/W F1 lupus mice decreases with methylprednisolone treatment.

9. The effect of in vivo hydrocortisone on subpopulations of human lymphocytes.

10. Effects of corticosteroids on immunity in man. I. Decreased serum IgG concentration caused by 3 or 5 days of high doses of methylprednisolone.